CD1D

GENERAL INFORMATION

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Gene name

CD1D

Gene description

CD1d molecule

Protein class

Cancer-related genes
CD markers
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (small intestine, spleen)

Protein evidence

Evidence at protein level

Protein localization

Normal tissues were weakly stained or negative. Neuronal cells, Leydig cells and subset of lymphoid cells showed moderate to strong positivity.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
CAB016107
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (small intestine, spleen)

Organ

Expression



GENE INFORMATION

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Gene name

CD1D

Synonyms

Description

CD1d molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q23.1

Chromosome location (bp)

158179947 - 158184896

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158473 (version 78.38)

Entrez gene

912

UniProt

P15813 (UniProt - Evidence at protein level)

neXtProt

NX_P15813

Antibodypedia

CD1D antibodies


PROTEIN BROWSER

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ENST00000368171
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD1D-001 ENSP00000357153
ENST00000368171
P15813
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Show » Show » 335 37.7 Yes 1