ARHGAP27

GENERAL INFORMATION

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Gene name

ARHGAP27

Gene description

Rho GTPase activating protein 27

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

A subset of cells in lymphoid tissues and inflammatory cells in the stroma were distinctly stained. Mucus secreting cells in bronchus and stomach, and exocrine pancreas showed moderate to strong cytoplasmic positivity. The remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA023919
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ARHGAP27 (HGNC Symbol)

Synonyms

CAMGAP1, FLJ43547, SH3D20, SH3P20

Description

Rho GTPase activating protein 27 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

45393902 - 45434421

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159314 (version 78.38)

Entrez gene

201176

UniProt

Q6ZUM4 (UniProt - Evidence at protein level)

neXtProt

NX_Q6ZUM4

Antibodypedia

ARHGAP27 antibodies


PROTEIN BROWSER

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ENST00000290470
 
ENST00000376922
 
ENST00000428638
 
ENST00000528273
 
ENST00000528384
 
ENST00000528677
 
ENST00000532038
 
ENST00000532891
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGAP27-001 ENSP00000366121
ENST00000376922
Q6ZUM4
Show all »
Show » Show » 548 61.7 No 0
ARHGAP27-003 ENSP00000432762
ENST00000532038
E9PNT2
Show all »
Show » Show » 667 75 No 0
ARHGAP27-004 ENSP00000437100
ENST00000528677
E9PNX6
Show all »
Show » Show » 214 23.4 No 0
ARHGAP27-006 ENSP00000431591
ENST00000528384
Q6ZUM4
Show all »
Show » Show » 521 58.4 No 0
ARHGAP27-009 ENSP00000433942
ENST00000532891
E9PIR1
Show all »
Show » Show » 867 96.1 No 0
ARHGAP27-011 ENSP00000436137
ENST00000528273
Q6ZUM4
Show all »
Show » Show » 263 28.2 No 0
ARHGAP27-201 ENSP00000290470
ENST00000290470
Q6ZUM4
Show all »
Show » Show » 263 28.2 No 0
ARHGAP27-202 ENSP00000403323
ENST00000428638
Q6ZUM4
Show all »
Show » Show » 889 98.4 No 0