PGLYRP3

GENERAL INFORMATION

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Gene name

PGLYRP3

Gene description

Peptidoglycan recognition protein 3

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (esophagus, skin)
GTEx:Group enriched (cervix, uterine, esophagus, skin, vagina)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Presumed off target binding observed and disregarded. Pending external verification. RNA data suggests expression in squamous epithelia.

Data reliability

Uncertain based on 1 antibody.
HPA030369
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (esophagus, skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cervix, uterine, esophagus, skin, vagina)

Organ

Expression



GENE INFORMATION

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Gene name

PGLYRP3 (HGNC Symbol)

Synonyms

PGLYRPIalpha, PGRP-Ialpha, PGRPIA

Description

Peptidoglycan recognition protein 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

153297862 - 153310718

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159527 (version 78.38)

Entrez gene

114771

UniProt

Q96LB9 (UniProt - Evidence at protein level)

neXtProt

NX_Q96LB9

Antibodypedia

PGLYRP3 antibodies


PROTEIN BROWSER

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ENST00000290722
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PGLYRP3-001 ENSP00000290722
ENST00000290722
Q96LB9
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