BNIPL

GENERAL INFORMATION

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Gene name

BNIPL

Gene description

BCL2/adenovirus E1B 19kD interacting protein like

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (esophagus, skin)
GTEx:Tissue enhanced (esophagus, skin)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in selected group of tissues, most abundant in skin. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA019946 , HPA023464
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (esophagus, skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (esophagus, skin)

Organ

Expression



GENE INFORMATION

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Gene name

BNIPL (HGNC Symbol)

Synonyms

BNIPl-1, BNIPL-2, PP753

Description

BCL2/adenovirus E1B 19kD interacting protein like (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

151036570 - 151047600

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163141 (version 78.38)

Entrez gene

149428

UniProt

Q7Z465 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z465

Antibodypedia

BNIPL antibodies


PROTEIN BROWSER

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ENST00000295294
 
ENST00000361277
 
ENST00000368931
 
ENST00000392802
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BNIPL-001 ENSP00000357927
ENST00000368931
Q7Z465
Show all »
Show » Show » 357 39.7 No 1
BNIPL-002 ENSP00000295294
ENST00000295294
Q7Z465
Show all »
Show » Show » 275 31 No 1
BNIPL-003 ENSP00000376550
ENST00000392802
F8W685
Show all »
Show » 100 11 No 0
BNIPL-006 ENSP00000355333
ENST00000361277
F8W685
Show all »
Show » 341 38.1 No 1