PGLYRP2

GENERAL INFORMATION

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Gene name

PGLYRP2

Gene description

Peptidoglycan recognition protein 2

Protein class

Enzymes
Plasma proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (liver)
GTEx:Tissue enriched (liver)

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression combined with positivity in plasma.

ANTIBODY RELIABILITY

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Data reliability
description

Presumed off target binding observed and disregarded. Pending external verification.

Data reliability

Uncertain based on 3 antibodies.
HPA043568 , HPA046311 , CAB033468
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (liver)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (liver)

Organ

Expression



GENE INFORMATION

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Gene name

PGLYRP2 (HGNC Symbol)

Synonyms

PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like

Description

Peptidoglycan recognition protein 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

15468645 - 15498956

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000161031 (version 78.38)

Entrez gene

114770

UniProt

Q96PD5 (UniProt - Evidence at protein level)

neXtProt

NX_Q96PD5

Antibodypedia

PGLYRP2 antibodies


PROTEIN BROWSER

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ENST00000292609
 
ENST00000340880
 
ENST00000594637
 
ENST00000601792
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PGLYRP2-001 ENSP00000345968
ENST00000340880
Q96PD5
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Show » Show » 576 62.2 Yes 0
PGLYRP2-002 ENSP00000292609
ENST00000292609
Q96PD5
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Show » Show » 634 68 Yes 0
PGLYRP2-003 ENSP00000472856
ENST00000601792
M0R2W8
Show all »
Show » Show » 181 19.5 No 1
PGLYRP2-004 ENSP00000470112
ENST00000594637
M0QYW3
Show all »
Show » Show » 105 11.4 Yes 0