COX18

GENERAL INFORMATION

? »

Gene name

COX18

Gene description

COX18 cytochrome C oxidase assembly factor

Protein class

Mitochondrial proteins
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in several tissues, high expression in cells in CNS.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA046772 , HPA049489
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

COX18 (HGNC Symbol)

Synonyms

FLJ38991

Description

COX18 cytochrome C oxidase assembly factor (HGNC Symbol)

Entrez gene summary

This gene encodes a cytochrome c oxidase assembly protein. The encoded protein is essential for integral membrane protein insertion into the mitochondrial inner membrane. It is also required for cytochrome c oxidase assembly and activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

4

Cytoband

q13.3

Chromosome location (bp)

73056080 - 73069755

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163626 (version 78.38)

Entrez gene

285521

UniProt

Q8N8Q8 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8N8Q8

Antibodypedia

COX18 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000295890
 
ENST00000507544
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX18-001 ENSP00000295890
ENST00000295890
Q8N8Q8
Show all »
Show » Show » 333 37.1 No 4
COX18-006 ENSP00000425261
ENST00000507544
B7ZL88
Show all »
Show » Show » 334 37.1 No 4