GMPS

GENERAL INFORMATION

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Gene name

GMPS

Gene description

Guanine monphosphate synthase

Protein class

Cancer-related genes
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

A subset of peripheral leukocytes, a small subset of cell in bone marrow and Purkinje cells displayed moderate or strong cytoplasmic staining. Remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA050682
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

GMPS

Synonyms

Description

Guanine monphosphate synthase (HGNC Symbol)

Entrez gene summary

In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q25.31

Chromosome location (bp)

155870536 - 155944026

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163655 (version 78.38)

Entrez gene

8833

UniProt

P49915 (UniProt - Evidence at protein level)

neXtProt

NX_P49915

Antibodypedia

GMPS antibodies


PROTEIN BROWSER

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ENST00000295920
 
ENST00000496455
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GMPS-001 ENSP00000419851
ENST00000496455
P49915
Show all »
Show » Show » 693 76.7 No 0
GMPS-002 ENSP00000295920
ENST00000295920
P49915
Show all »
Show » Show » 594 65.9 No 0