PEX2

GENERAL INFORMATION

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Gene name

PEX2

Gene description

Peroxisomal biogenesis factor 2

Protein class

Disease related genes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA011410 , HPA027729
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PEX2 (HGNC Symbol)

Synonyms

PAF-1, PMP35, PXMP3, RNF72, ZWS3

Description

Peroxisomal biogenesis factor 2 (HGNC Symbol)

Entrez gene summary

This gene encodes an integral peroxisomal membrane protein required for peroxisome biogenesis. The protein is thought to be involved in peroxisomal matrix protein import. Mutations in this gene result in one form of Zellweger syndrome and infantile Refsum disease. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q21.13

Chromosome location (bp)

76980258 - 77001044

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164751 (version 78.38)

Entrez gene

5828

UniProt

P28328 (UniProt - Evidence at protein level)

neXtProt

NX_P28328

Antibodypedia

PEX2 antibodies


PROTEIN BROWSER

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ENST00000357039
 
ENST00000518986
 
ENST00000519956
 
ENST00000520103
 
ENST00000522527
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PEX2-001 ENSP00000349543
ENST00000357039
P28328
Show all »
Show » Show » 305 34.8 No 1
PEX2-002 ENSP00000428638
ENST00000522527
P28328
Show all »
Show » Show » 305 34.8 No 1
PEX2-003 ENSP00000428590
ENST00000520103
P28328
Show all »
Show » Show » 305 34.8 No 1
PEX2-004 ENSP00000429740
ENST00000519956
Show » 3 0.3 No 0
PEX2-006 ENSP00000429304
ENST00000518986
E5RIW9
Show all »
Show » 180 20.8 No 1