PNPLA4

GENERAL INFORMATION

? »

Gene name

PNPLA4

Gene description

Patatin-like phospholipase domain containing 4

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA003656
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

PNPLA4 (HGNC Symbol)

Synonyms

DXS1283E, GS2, iPLA2eta

Description

Patatin-like phospholipase domain containing 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Feb 2010]

Chromosome

X

Cytoband

p22.31

Chromosome location (bp)

7898247 - 7927739

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006757 (version 78.38)

Entrez gene

8228

UniProt

P41247 (UniProt - Evidence at transcript level)

neXtProt

NX_P41247

Antibodypedia

PNPLA4 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000381042
 
ENST00000442940
 
ENST00000444736
 
ENST00000537427
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PNPLA4-002 ENSP00000406698
ENST00000442940
C9IZF6
Show all »
Show » Show » 190 20.6 Yes 0
PNPLA4-003 ENSP00000370430
ENST00000381042
P41247
Show all »
Show » Show » 253 28 Yes 0
PNPLA4-201 ENSP00000415245
ENST00000444736
P41247
Show all »
Show » Show » 253 28 Yes 0
PNPLA4-202 ENSP00000443157
ENST00000537427
P41247
Show all »
Show » Show » 166 18.6 No 0