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PNPLA4
BASAL GANGLIA - Expression summary
Protein expression
Caudatei
h
m
l
n
Glial cells: Medium
Neuronal cells: Low
RNA expressioni
Consensus:12.3 nTPM
HPA:12.3 nTPM
GTEx:16.3 nTPM
FANTOM5:31.2 Scaled Tags Per Million
Pig:3.0 nTPM

CAUDATE - Antibody stainingi
Antibody HPA003656
Glial cells Medium
Neuronal cells Low



BASAL GANGLIA - HPA Brain RNA-seq
Max nTPM 12.3
Sample id Sample description nTPM
Caudate nucleus
nTPM: 12.3
2302 Male, age 61, right hemisphere 14.8
1857 Female, age 85, left hemisphere 14.6
2481 Female, age 94, left hemisphere 14.0
2846 Female, age 79, unknown 12.6
1854 Male, age 80, left hemisphere 12.2
2713 Male, age 75, left hemisphere 11.7
2301 Female, age 72, unknown 11.6
1781 Male, age 74, unknown 9.9
2306 Female, age 91, right hemisphere 8.8
Claustrum
nTPM: 9.0
2299 Female, age 85, both hemispheres 10.4
2196 Female, age 79, unknown 9.6
2568 Male, age 61, both hemispheres 9.6
2198 Male, age 80, both hemispheres 9.3
1956 Male, age 74, unknown 9.1
2645 Female, age 72, unknown 8.8
2491 Male, age 75, both hemispheres 8.5
2307 Female, age 91, both hemispheres 8.1
2392 Female, age 94, both hemispheres 8.0
Globus pallidus, externus
nTPM: 10.5
1996 Male, age 80, right hemisphere 11.6
2644 Female, age 94, right hemisphere 11.6
2646 Male, age 61, right hemisphere 11.1
2772 Female, age 79, unknown 10.9
2395 Male, age 75, both hemispheres 10.2
2114 Female, age 85, right hemisphere 10.0
2011 Female, age 91, left hemisphere 9.4
2567 Female, age 72, unknown 9.1
Globus pallidus, internus
nTPM: 10.7
2483 Female, age 94, right hemisphere 13.2
2037 Male, age 80, right hemisphere 11.8
1997 Male, age 61, left hemisphere 11.3
2714 Male, age 75, right hemisphere 10.6
1818 Male, age 74, unknown 10.5
2778 Female, age 91, both hemispheres 10.5
2566 Female, age 72, unknown 9.3
2111 Female, age 85, right hemisphere 8.4
Nucleus accumbens
nTPM: 12.1
1856 Female, age 91, right hemisphere 16.0
1806 Female, age 85, left hemisphere 14.1
1783 Male, age 74, unknown 12.1
2698 Female, age 72, unknown 11.5
2824 Male, age 61, right hemisphere 11.5
2305 Male, age 75, left hemisphere 10.8
2391 Female, age 94, left hemisphere 10.7
2732 Male, age 80, right hemisphere 10.6
Nucleus basalis of Meynert
nTPM: 10.7
2569 Male, age 61, both hemispheres 12.7
2393 Male, age 80, right hemisphere 11.9
2842 Male, age 74, unknown 10.8
2484 Female, age 94, left hemisphere 10.5
2821 Male, age 75, both hemispheres 10.0
2300 Female, age 85, both hemispheres 9.9
2200 Female, age 91, left hemisphere 9.0
Nucleus of the diagonal band
nTPM: 10.9
1979 Male, age 74, unknown 12.8
2775 Male, age 80, right hemisphere 11.2
2195 Female, age 85, both hemispheres 10.7
2029 Male, age 61, right hemisphere 10.1
1812 Female, age 91, both hemispheres 10.0
Olfactory tubercle
nTPM: 10.3
1846 Male, age 80, right hemisphere 12.1
2856 Male, age 75, right hemisphere 10.6
2487 Female, age 94, left hemisphere 9.4
1998 Female, age 91, both hemispheres 9.3
Putamen
nTPM: 11.7
1838 Male, age 80, right hemisphere 13.7
1937 Female, age 91, right hemisphere 13.4
2466 Female, age 79, unknown 13.0
2482 Female, age 94, left hemisphere 12.9
1829 Male, age 74, unknown 11.2
2490 Male, age 61, left hemisphere 11.2
2489 Female, age 72, unknown 10.6
2488 Female, age 85, left hemisphere 9.7
2647 Male, age 75, left hemisphere 9.5
Septal nuclei
nTPM: 10.3
2199 Male, age 80, right hemisphere 11.7
1960 Male, age 74, unknown 10.8
2009 Female, age 91, both hemispheres 10.5
2394 Male, age 61, left hemisphere 10.2
2059 Female, age 85, both hemispheres 9.8
2629 Female, age 94, right hemisphere 9.8
2031 Female, age 72, unknown 9.4

BASAL GANGLIA - GTEx RNA-seqi
Max average nTPM 16.3
GTEx sample id Sample description nTPM
Brain - Caudate (basal ganglia)
Average nTPM: 15.6
Samples: 246

Max nTPM: 34.8
Min nTPM: 7.6
Std nTPM: 4.5
Median nTPM: 14.7
GTEX-17HG3-0011-R5a-SM-7DUEW 30-39 years, female 34.8
GTEX-14LZ3-0011-R5b-SM-5ZZV8 60-69 years, female 34.5
GTEX-14JG1-0011-R5a-SM-62LED 40-49 years, male 26.9
GTEX-1J1OQ-0011-R5a-SM-D3L8K 40-49 years, female 26.3
GTEX-1B933-0011-R5b-SM-7P8SA 50-59 years, female 25.7
GTEX-14JIY-0011-R5b-SM-62LE7 60-69 years, male 25.4
GTEX-1CB4H-0011-R5b-SM-9QEGN 60-69 years, female 24.8
GTEX-QVJO-0011-R5A-SM-2S1QM 60-69 years, female 24.7
GTEX-ZVZQ-0011-R5b-SM-57WDC 60-69 years, female 24.7
GTEX-17EVP-0011-R5b-SM-7DHKW 40-49 years, male 24.5
GTEX-1R9PO-0011-R5a-SM-EZ6NA 60-69 years, female 24.3
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Brain - Nucleus accumbens (basal ganglia)
Average nTPM: 16.3
Samples: 246

Max nTPM: 39.2
Min nTPM: 7.0
Std nTPM: 4.5
Median nTPM: 15.6
GTEX-1F88E-0011-R6a-SM-CKZNW 60-69 years, female 39.2
GTEX-QVUS-0011-R6A-SM-3GACX 60-69 years, female 30.3
GTEX-14LZ3-0011-R6a-SM-D3L8C 60-69 years, female 29.5
GTEX-TSE9-0011-R6A-SM-3DB7L 60-69 years, female 26.9
GTEX-1OJC4-0011-R6a-SM-EXOIM 50-59 years, female 26.5
GTEX-ZVT3-0011-R6a-SM-51MSU 60-69 years, female 25.9
GTEX-1GMR8-0011-R6b-SM-CE6RC 50-59 years, female 25.5
GTEX-T2IS-0011-R6A-SM-32QP2 20-29 years, female 24.8
GTEX-11TTK-0011-R6b-SM-DNZZW 60-69 years, female 24.8
GTEX-15ER7-0011-R6a-SM-6M46M 20-29 years, female 24.5
GTEX-13X6K-0011-R6a-SM-5P9K6 60-69 years, female 24.2
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Brain - Putamen (basal ganglia)
Average nTPM: 14.7
Samples: 205

Max nTPM: 41.9
Min nTPM: 6.9
Std nTPM: 4.3
Median nTPM: 14.1
GTEX-13CF2-0011-R7b-SM-5K7UV 60-69 years, male 41.9
GTEX-1IKOH-0011-R7b-SM-CKZPH 60-69 years, female 27.9
GTEX-QVJO-0011-R7A-SM-2S1QO 60-69 years, female 27.0
GTEX-ZV68-0011-R7a-SM-51MT4 50-59 years, female 26.3
GTEX-1LVA9-0011-R7a-SM-EYYWG 50-59 years, male 25.8
GTEX-1F52S-0011-R7b-SM-9QEH8 60-69 years, female 24.5
GTEX-14LZ3-0011-R7a-SM-69LQN 60-69 years, female 24.3
GTEX-11GSP-0011-R7b-SM-57WC3 60-69 years, female 23.8
GTEX-ZVT3-0011-R7a-SM-57WCO 60-69 years, female 23.8
GTEX-131YS-0011-R7a-SM-5IJDA 60-69 years, female 23.6
GTEX-1H1CY-0011-R7a-SM-CJI32 60-69 years, female 22.5
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BASAL GANGLIA - FANTOM5 CAGEi
Max Scaled Tags Per Million 31.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Caudate nucleus
Scaled Tags Per Million: 27.3
FF:10164-103B2 76 years, female 27.3
Nucleus accumbens
Scaled Tags Per Million: 20.4
FF:10037-101F1 23-56 years, mixed 20.4
Putamen
Scaled Tags Per Million: 31.2
FF:10176-103C5 60 years, female 31.2

BASAL GANGLIA - Pig RNA-seqi
Average nTPM 3.0
Pig sample Sample description nTPM
Caudate
nTPM: 2.6
Samples: 4

Max nTPM: 3.5
Min nTPM: 1.5
Sample A Female 1.9
Sample B Female 3.5
Sample C Male 1.5
Sample D Male 3.5
Putamen
nTPM: 3.0
Samples: 4

Max nTPM: 3.9
Min nTPM: 2.4
Sample A Female 3.3
Sample B Female 2.5
Sample C Male 2.4
Sample D Male 3.9
Septum
nTPM: 2.2
Samples: 4

Max nTPM: 3.9
Min nTPM: 0.7
Sample A Female 3.9
Sample B Female 1.1
Sample C Male 3.0
Sample D Male 0.7
Ventral pallidum
nTPM: 2.8
Samples: 4

Max nTPM: 3.3
Min nTPM: 2.1
Sample A Female 3.3
Sample B Female 2.8
Sample C Male 2.9
Sample D Male 2.1

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