NLGN4Y

GENERAL INFORMATION

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Gene name

NLGN4Y

Gene description

Neuroligin 4, Y-linked

Protein class

Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at transcript level

Protein localization

Cytoplasmic positivity in CNS and peripheral ganglia.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene.

Data reliability

Uncertain based on 1 antibody.
HPA001651
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

NLGN4Y (HGNC Symbol)

Synonyms

KIAA0951

Description

Neuroligin 4, Y-linked (HGNC Symbol)

Entrez gene summary

This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]

Chromosome

Y

Cytoband

q11.221

Chromosome location (bp)

14522638 - 14845650

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000165246 (version 78.38)

Entrez gene

22829

UniProt

Q8NFZ3 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NFZ3

Antibodypedia

NLGN4Y antibodies


PROTEIN BROWSER

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ENST00000297967
 
ENST00000339174
 
ENST00000355905
 
ENST00000382868
 
ENST00000382872
 
ENST00000413217
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NLGN4Y-001 ENSP00000372325
ENST00000382872
Q8NFZ3
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Show » Show » 648 72.9 No 1
NLGN4Y-002 ENSP00000348169
ENST00000355905
Q8NFZ3
Show all »
Show » Show » 816 92 Yes 1
NLGN4Y-003 ENSP00000372320
ENST00000382868
A6NMU8
Show all »
Show » Show » 873 98.5 Yes 1
NLGN4Y-005 ENSP00000342535
ENST00000339174
Q8NFZ3
Show all »
Show » Show » 816 92 Yes 1
NLGN4Y-006 ENSP00000412638
ENST00000413217
Show » 236 26.5 Yes 0
NLGN4Y-201 ENSP00000297967
ENST00000297967
Q8NFZ3
Show all »
Show » Show » 256 28.9 Yes 0