OTUD7A

GENERAL INFORMATION

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Gene name

OTUD7A

Gene description

OTU deubiquitinase 7A

Protein class

Cancer-related genes
Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex)
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic and nuclear expression. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA044554
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

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Gene name

OTUD7A (HGNC Symbol)

Synonyms

C15orf16, CEZANNE2, OTUD7

Description

OTU deubiquitinase 7A (HGNC Symbol)

Entrez gene summary

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]

Chromosome

15

Cytoband

q13.3

Chromosome location (bp)

31475398 - 31870789

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169918 (version 78.38)

Entrez gene

161725

UniProt

Q8TE49 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TE49

Antibodypedia

OTUD7A antibodies


PROTEIN BROWSER

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ENST00000307050
 
ENST00000560598
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OTUD7A-001 ENSP00000305926
ENST00000307050
Q8TE49
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Show » Show » 926 100.7 No 0
OTUD7A-004 ENSP00000453883
ENST00000560598
H0YN66
Show all »
Show » Show » 110 12.2 No 0