KSR2

GENERAL INFORMATION

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Gene name

KSR2

Gene description

Kinase suppressor of ras 2

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex)
GTEx:Group enriched (cerebellum, cerebral cortex, hippocampus, testis)

Protein evidence

Evidence at protein level

Protein localization

Most of the normal tissues displayed weak to moderate nucleolar and/or cytoplasmic positivity. Strong staining was observed in Purkinje cells and cells in molecular layer. Bile ducts, glandular cells in male genital tract, glial cells and lymphoid tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA035536
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebellum, cerebral cortex, hippocampus, testis)

Organ

Expression



GENE INFORMATION

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Gene name

KSR2 (HGNC Symbol)

Synonyms

FLJ25965

Description

Kinase suppressor of ras 2 (HGNC Symbol)

Entrez gene summary

Chromosome

12

Cytoband

Chromosome location (bp)

117453012 - 117968983

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171435 (version 78.38)

Entrez gene

283455

UniProt

Q6VAB6 (UniProt - Evidence at protein level)

neXtProt

NX_Q6VAB6

Antibodypedia

KSR2 antibodies


PROTEIN BROWSER

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ENST00000339824
 
ENST00000425217
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KSR2-001 ENSP00000339952
ENST00000339824
Q6VAB6
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Show » Show » 950 107.6 No 0
KSR2-201 ENSP00000389715
ENST00000425217
E9PB13
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Show » Show » 921 104.3 No 0