MKRN3

GENERAL INFORMATION

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Gene name

MKRN3

Gene description

Makorin ring finger protein 3

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex, placenta)
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in most cell types.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA029494
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, placenta)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

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Gene name

MKRN3 (HGNC Symbol)

Synonyms

D15S9, MGC88288, RNF63, ZFP127, ZNF127

Description

Makorin ring finger protein 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q11.2

Chromosome location (bp)

23565678 - 23630075

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000179455 (version 78.38)

Entrez gene

7681

UniProt

Q13064 (UniProt - Evidence at protein level)

neXtProt

NX_Q13064

Antibodypedia

MKRN3 antibodies


PROTEIN BROWSER

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ENST00000314520
 
ENST00000564592
 
ENST00000568252
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MKRN3-001 ENSP00000313881
ENST00000314520
Q13064
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Show » Show » 507 55.6 No 0
MKRN3-003 ENSP00000455368
ENST00000564592
H3BPL3
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Show » 182 19.6 No 0
MKRN3-005 ENSP00000456779
ENST00000568252
Q6NSB6
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Show » 105 10.5 No 0