MUC16

GENERAL INFORMATION

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Gene name

MUC16

Gene description

Mucin 16, cell surface associated

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (endometrium, fallopian tube)
GTEx:Tissue enhanced (adipose tissue, cervix, uterine, salivary gland)

Protein evidence

Evidence at protein level

Protein localization

Selective expression in mucinous cells of respiratory epithelia, salivary gland and cervix. Membranous expression in glandular cells of fallopian tube, uterus and ductal cells in salivary gland.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
CAB055172
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Endometrium



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (endometrium, fallopian tube)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (adipose tissue, cervix, uterine, salivary gland)

Organ

Expression



GENE INFORMATION

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Gene name

MUC16 (HGNC Symbol)

Synonyms

CA125, FLJ14303

Description

Mucin 16, cell surface associated (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

8848844 - 8981342

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000181143 (version 78.38)

Entrez gene

94025

UniProt

neXtProt

Antibodypedia

MUC16 antibodies


PROTEIN BROWSER

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ENST00000397910
 
ENST00000599436
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MUC16-001 ENSP00000381008
ENST00000397910
B5ME49
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Show » Show » 14507 1519.2 No 1
MUC16-004 ENSP00000472781
ENST00000599436
Show » 1330 148.2 No 1