CNTN2

GENERAL INFORMATION

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Gene name

CNTN2

Gene description

Contactin 2 (axonal)

Protein class

Disease related genes
Plasma proteins
Potential drug targets
Predicted secreted proteins
Transporters

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Tissue enhanced (cerebellum, cerebral cortex, hippocampus)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in CNS.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Data reliability

Uncertain based on 2 antibodies.
HPA001397 , HPA012497
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum, cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

CNTN2 (HGNC Symbol)

Synonyms

AXT, TAG-1, TAX, TAX1

Description

Contactin 2 (axonal) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q32.1

Chromosome location (bp)

205043197 - 205078499

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184144 (version 78.38)

Entrez gene

6900

UniProt

Q02246 (UniProt - Evidence at protein level)

neXtProt

NX_Q02246

Antibodypedia

CNTN2 antibodies


PROTEIN BROWSER

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ENST00000331830
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CNTN2-001 ENSP00000330633
ENST00000331830
Q02246
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