SRPK3

GENERAL INFORMATION

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Gene name

SRPK3

Gene description

SRSF protein kinase 3

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (heart muscle, skeletal muscle)
GTEx:Tissue enhanced (skeletal muscle)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in a selected group of tissues, most abundant in skeletal muscle. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA042489
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (heart muscle, skeletal muscle)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (skeletal muscle)

Organ

Expression



GENE INFORMATION

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Gene name

SRPK3 (HGNC Symbol)

Synonyms

MSSK1, STK23

Description

SRSF protein kinase 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Chromosome

X

Cytoband

q28

Chromosome location (bp)

153776412 - 153785732

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184343 (version 78.38)

Entrez gene

26576

UniProt

Q9UPE1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UPE1

Antibodypedia

SRPK3 antibodies


PROTEIN BROWSER

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ENST00000370100
 
ENST00000370101
 
ENST00000370104
 
ENST00000370108
 
ENST00000393786
 
ENST00000430541
 
ENST00000458681
 
ENST00000489426
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRPK3-001 ENSP00000359126
ENST00000370108
A8MPY5
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Show » Show » 534 59.1 No 0
SRPK3-002 ENSP00000359118
ENST00000370100
A8MPP7
Show all »
Show » Show » 492 55.4 No 0
SRPK3-003 ENSP00000402300
ENST00000430541
Show » Show » 205 22.3 No 0
SRPK3-004 ENSP00000406166
ENST00000458681
Show » Show » 129 14.7 No 0
SRPK3-005 ENSP00000359122
ENST00000370104
Q9UPE1
Show all »
Show » Show » 566 61.9 No 0
SRPK3-006 ENSP00000359119
ENST00000370101
Q9UPE1
Show all »
Show » Show » 567 62 No 0
SRPK3-007 ENSP00000420058
ENST00000489426
E7ETV6
Show all »
Show » Show » 634 69.2 No 0
SRPK3-201 ENSP00000377376
ENST00000393786
Q9UPE1
Show all »
Show » Show » 533 59 No 0