CSF2RA

GENERAL INFORMATION

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Gene name

CSF2RA

Gene description

Colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

Protein class

Cancer-related genes
CD markers
Disease related genes
FDA approved drug targets
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

12
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (placenta)
GTEx:Tissue enhanced (spleen)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Presumed off target binding observed and disregarded. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
CAB016148
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (placenta)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (spleen)

Organ

Expression



GENE INFORMATION

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Gene name

CSF2RA (HGNC Symbol)

Synonyms

CD116, CSF2R

Description

Colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p22.33

Chromosome location (bp)

1268800 - 1310381

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198223 (version 78.38)

Entrez gene

1438

UniProt

P15509 (UniProt - Evidence at protein level)

neXtProt

NX_P15509

Antibodypedia

CSF2RA antibodies


PROTEIN BROWSER

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ENST00000355432
 
ENST00000355805
 
ENST00000381500
 
ENST00000381509
 
ENST00000381524
 
ENST00000381529
 
ENST00000412290
 
ENST00000417535
 
ENST00000419094
 
ENST00000432318
 
ENST00000494969
 
ENST00000501036
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CSF2RA-001 ENSP00000370935
ENST00000381524
P15509
Show all »
Show » Show » 400 46.2 Yes 1
CSF2RA-002 ENSP00000348058
ENST00000355805
P15509
Show all »
Show » Show » 233 26.6 Yes 0
CSF2RA-004 ENSP00000347606
ENST00000355432
P15509
Show all »
Show » Show » 377 43.5 Yes 0
CSF2RA-005 ENSP00000370920
ENST00000381509
P15509
Show all »
Show » Show » 410 46.9 Yes 1
CSF2RA-006 ENSP00000370940
ENST00000381529
P15509
Show all »
Show » Show » 400 46.2 Yes 1
CSF2RA-007 ENSP00000370911
ENST00000381500
P15509
Show all »
Show » Show » 333 38.4 Yes 0
CSF2RA-009 ENSP00000410667
ENST00000412290
J3JS74
Show all »
Show » Show » 238 27.4 Yes 0
CSF2RA-010 ENSP00000397452
ENST00000419094
J3JS73
Show all »
Show » Show » 188 21.5 Yes 0
CSF2RA-012 ENSP00000476684
ENST00000494969
V9GYE9
Show all »
Show » 90 10.2 Yes 0
CSF2RA-201 ENSP00000394227
ENST00000417535
P15509
Show all »
Show » Show » 434 49.9 Yes 1
CSF2RA-202 ENSP00000416437
ENST00000432318
P15509
Show all »
Show » Show » 400 46.2 Yes 1
CSF2RA-203 ENSP00000440491
ENST00000501036
P15509
Show all »
Show » Show » 267 31.1 No 1