DEFB135

GENERAL INFORMATION

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Gene name

DEFB135

Gene description

Defensin, beta 135

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Not detected
GTEx:Not detected

Protein evidence

No evidence

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

No RNA expression data detected and pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Data reliability

Uncertain based on 1 antibody.
HPA044176
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Small intestine

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Not detected

Organ

Expression

GTEx dataset
RNA tissue category:  Not detected

Organ

Expression



GENE INFORMATION

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Gene name

DEFB135

Synonyms

Description

Defensin, beta 135 (HGNC Symbol)

Entrez gene summary

Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 8p23. [provided by RefSeq, Nov 2014]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

11982321 - 11984590

Protein evidence

No evidence (all genes)

Ensembl

ENSG00000205883 (version 78.38)

Entrez gene

613209

UniProt

Q30KP9 (UniProt - Inferred from homology)

neXtProt

NX_Q30KP9

Antibodypedia

DEFB135 antibodies


PROTEIN BROWSER

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ENST00000382208
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEFB135-001 ENSP00000371643
ENST00000382208
Q30KP9
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Show » Show » 77 8.8 Yes 0