CGB8

GENERAL INFORMATION

? »

Gene name

CGB8

Gene description

Chorionic gonadotropin, beta polypeptide 8

Protein class

Cancer-related genes
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enriched (placenta)
GTEx:Not detected

Protein evidence

Evidence at protein level

Protein localization

Selective cytoplasmic expression in placental trophoblasts.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining consistent with RNA expression data. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 2 antibodies.
HPA038925 , HPA038934
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enriched (placenta)

Organ

Expression

GTEx dataset
RNA tissue category:  Not detected

Organ

Expression



GENE INFORMATION

? »

Gene name

CGB8

Synonyms

Description

Chorionic gonadotropin, beta polypeptide 8 (HGNC Symbol)

Entrez gene summary

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49047638 - 49049106

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000213030 (version 78.38)

Entrez gene

94115

UniProt

P01233 (UniProt - Evidence at transcript level,UniProt - Evidence at protein level), Q6NT52 (UniProt - Evidence at transcript level,UniProt - Evidence at protein level)

neXtProt

NX_P01233, NX_Q6NT52

Antibodypedia

CGB8 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000448456
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CGB8-001 ENSP00000403649
ENST00000448456
P01233
Show all »
Show » Show » 165 17.7 Yes 0