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BETA
  • SUMMARY

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  • BRAIN

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  • MAP2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:92.2 nTPM
HPA Brain:418.4 nTPM
GTEx:92.2 nTPM
FANTOM5:46.4 Scaled Tags Per Million
Macaque:442.7 nTPM
Mouse:532.4 nTPM
Rat:379.9 nTPM
Pig:553.3 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 1410
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 2080
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

418.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 210.0
1827 Male, age 72, unknown 278.7
2219 Male, age 76, both hemispheres 267.8
2666 Male, age 74, left hemisphere 242.9
1870 Female, age 42, unknown 221.3
2411 Female, age 72, unknown 202.3
2828 Female, age 72, unknown 196.4
1833 Male, age 53, unknown 191.8
2586 Male, age 75, left hemisphere 168.7
2019 Male, age 18, unknown 166.4
1830 Male, age 51, unknown 164.0
Dorsal raphe nucleus
nTPM: 266.9
2298 Female, age 72, unknown 341.0
2047 Male, age 72, unknown 282.9
1828 Male, age 53, unknown 265.8
2750 Male, age 76, both hemispheres 250.1
2016 Female, age 72, unknown 194.5
Inferior colliculus
nTPM: 278.1
2097 Female, age 72, unknown 330.2
2849 Male, age 72, unknown 284.9
1848 Female, age 42, unknown 276.7
1890 Male, age 53, unknown 220.5
Median raphe nucleus
nTPM: 418.4
2220 Male, age 76, midline 418.4
Periaquaductal grey, anterior
nTPM: 268.6
2502 Female, age 75, unknown 311.1
1795 Male, age 51, unknown 261.8
1947 Male, age 18, unknown 233.1
Periaquaductal grey, dorsal
nTPM: 246.7
1840 Male, age 53, unknown 318.7
2850 Male, age 76, both hemispheres 247.3
2464 Female, age 72, unknown 211.9
1831 Male, age 72, unknown 209.0
Periaquaductal grey, lateral
nTPM: 211.2
2053 Male, age 18, unknown 225.1
2140 Male, age 76, both hemispheres 220.9
2272 Male, age 74, both hemispheres 187.5
Pretectal area
nTPM: 253.9
1816 Male, age 51, unknown 342.7
2224 Female, age 72, unknown 334.7
1944 Female, age 72, unknown 318.3
1817 Female, age 42, unknown 275.0
2007 Male, age 72, unknown 257.8
2825 Male, age 18, unknown 254.8
1815 Male, age 53, unknown 242.2
2667 Female, age 75, unknown 221.2
2316 Male, age 76, right hemisphere 187.7
2407 Male, age 75, both hemispheres 185.2
2273 Male, age 74, both hemispheres 173.8
Red nucleus
nTPM: 133.8
2584 Male, age 75, left hemisphere 181.8
1821 Female, age 72, unknown 160.8
2785 Male, age 18, unknown 159.5
2227 Male, age 72, unknown 139.5
2725 Female, age 75, unknown 138.8
2769 Male, age 72, unknown 135.6
2503 Female, age 72, unknown 127.4
1954 Female, age 42, unknown 121.9
2823 Male, age 76, right hemisphere 116.6
2588 Male, age 74, left hemisphere 112.8
1865 Male, age 51, unknown 109.4
1904 Male, age 53, unknown 101.9
Substantia nigra
nTPM: 263.7
1916 Female, age 42, unknown 366.6
1941 Male, age 53, unknown 318.5
2241 Male, age 72, unknown 311.7
2665 Male, age 74, both hemispheres 292.9
1889 Female, age 72, unknown 280.5
1851 Male, age 51, unknown 271.8
2409 Female, age 72, unknown 260.6
2699 Male, age 18, unknown 238.4
2590 Female, age 75, unknown 149.8
2583 Male, age 75, right hemisphere 146.5
Superior colliculus
nTPM: 229.5
2668 Female, age 75, unknown 340.7
1895 Male, age 76, right hemisphere 278.6
2087 Female, age 72, unknown 267.3
1796 Male, age 53, unknown 258.6
2261 Male, age 18, unknown 250.7
1839 Male, age 51, unknown 236.0
2664 Male, age 75, both hemispheres 209.1
2587 Male, age 74, left hemisphere 173.3
1913 Female, age 42, unknown 157.8
1995 Male, age 72, unknown 122.5
Ventral tegmental area
nTPM: 261.3
2218 Male, age 76, both hemispheres 316.2
1915 Female, age 42, unknown 287.3
1942 Male, age 51, unknown 253.0
2410 Female, age 72, unknown 238.3
2223 Female, age 72, unknown 236.7
2021 Male, age 53, unknown 236.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

92.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 92.2
Samples: 183

Max nTPM: 406.7
Min nTPM: 7.0
Std nTPM: 79.6
Median nTPM: 61.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 406.7
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 385.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 332.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 301.1
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 282.1
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 279.5
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 278.2
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 265.4
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 258.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 253.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 253.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 251.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 246.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 233.9
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 230.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 225.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 224.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 223.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 213.9
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 207.8
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 201.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 195.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 194.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 191.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 189.3
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 187.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 184.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 179.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 171.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 164.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 161.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 153.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 153.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 153.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 150.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 149.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 147.0
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 146.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 146.2
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 142.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 141.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 140.5
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 140.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 139.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 137.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 135.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 132.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 130.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 126.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 124.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 122.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 119.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 117.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 114.8
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 109.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 108.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 107.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 106.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 106.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 106.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 106.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 104.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 104.3
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 101.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 100.7
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 100.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 97.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 96.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 95.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 95.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 95.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 94.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 88.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 85.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 81.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 81.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 79.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 78.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 78.5
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 78.5
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 74.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 74.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 74.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 72.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 69.3
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 67.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 66.7
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 66.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 66.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 64.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 63.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 61.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 61.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 60.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 60.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 59.5
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 59.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 59.1
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 57.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 57.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 56.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 56.1
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 53.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 52.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 51.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 51.2
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 50.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 50.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 47.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 47.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 46.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 46.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 46.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 45.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 45.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 44.2
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 44.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 41.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 41.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 40.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 38.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 38.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 37.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 36.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 36.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 35.6
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 35.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 35.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 35.4
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 34.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 34.5
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 34.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 34.3
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 34.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 32.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 32.6
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 32.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 31.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 30.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 29.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 28.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 28.5
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 28.3
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 27.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 27.9
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 27.6
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 27.0
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 27.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 26.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 26.7
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 26.4
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 25.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 25.4
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 24.3
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 24.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 23.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 23.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 22.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 22.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 21.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 21.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 20.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 20.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 19.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 18.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 18.6
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 18.6
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 18.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 18.1
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 16.8
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 16.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 15.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 15.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 13.4
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 13.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 12.6
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 10.6
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 10.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 9.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 8.9
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 7.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

46.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 46.4
FF:10158-103A5 76 years, female 46.4

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

442.7
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 356.0
Samples: 1

Max nTPM: 356.0
Min nTPM: 356.0
Sample A 356.0
Midbrain
nTPM: 428.0
Samples: 1

Max nTPM: 428.0
Min nTPM: 428.0
Sample A 428.0
Superior colliculi
nTPM: 442.7
Samples: 1

Max nTPM: 442.7
Min nTPM: 442.7
Sample A 442.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

553.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 336.6
Samples: 3

Max nTPM: 424.6
Min nTPM: 222.7
Sample A Female 362.5
Sample B Female 222.7
Sample C Male 424.6
Midbrain
nTPM: 553.3
Samples: 3

Max nTPM: 617.1
Min nTPM: 461.4
Sample B Female 461.4
Sample C Male 581.3
Sample D Male 617.1
Periaqueductal gray
nTPM: 395.1
Samples: 3

Max nTPM: 449.7
Min nTPM: 309.9
Sample B Female 449.7
Sample C Male 425.6
Sample D Male 309.9
Superior colliculi
nTPM: 379.4
Samples: 4

Max nTPM: 502.0
Min nTPM: 201.3
Sample A Female 412.8
Sample B Female 201.3
Sample C Male 401.6
Sample D Male 502.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

532.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 532.5
Samples: 4

Max nTPM: 583.7
Min nTPM: 487.5
Sample A 487.5
Sample B 505.0
Sample C 553.6
Sample D 583.7

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

379.9
Rat sample Sample description nTPM
Midbrain
nTPM: 379.9
Samples: 4

Max nTPM: 388.0
Min nTPM: 369.4
Sample A 369.4
Sample A 388.0
Sample A 383.5
Sample A 378.7

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