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BETA
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:1156.5 nTPM
HPA Brain:753.3 nTPM
GTEx:1156.5 nTPM
FANTOM5:1158.3 Scaled Tags Per Million
Macaque:2.8 nTPM
Mouse:611.4 nTPM
Rat:496.5 nTPM
Pig:1067.0 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 110
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 60
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

753.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 592.2
2019 Male, age 18, unknown 817.3
1870 Female, age 42, unknown 704.9
2411 Female, age 72, unknown 699.9
1827 Male, age 72, unknown 661.4
1833 Male, age 53, unknown 572.1
1830 Male, age 51, unknown 538.8
2828 Female, age 72, unknown 519.3
2219 Male, age 76, both hemispheres 491.5
2666 Male, age 74, left hemisphere 485.6
2586 Male, age 75, left hemisphere 431.4
Dorsal raphe nucleus
nTPM: 594.6
2298 Female, age 72, unknown 674.1
2750 Male, age 76, both hemispheres 657.3
1828 Male, age 53, unknown 603.5
2047 Male, age 72, unknown 547.6
2016 Female, age 72, unknown 490.7
Inferior colliculus
nTPM: 570.3
2097 Female, age 72, unknown 710.0
1848 Female, age 42, unknown 550.6
1890 Male, age 53, unknown 548.1
2849 Male, age 72, unknown 472.5
Median raphe nucleus
nTPM: 573.0
2220 Male, age 76, midline 573.0
Periaquaductal grey, anterior
nTPM: 641.0
1947 Male, age 18, unknown 664.9
2502 Female, age 75, unknown 655.8
1795 Male, age 51, unknown 602.2
Periaquaductal grey, dorsal
nTPM: 534.6
1831 Male, age 72, unknown 543.9
2464 Female, age 72, unknown 543.8
1840 Male, age 53, unknown 531.4
2850 Male, age 76, both hemispheres 519.3
Periaquaductal grey, lateral
nTPM: 545.0
2053 Male, age 18, unknown 592.8
2272 Male, age 74, both hemispheres 568.5
2140 Male, age 76, both hemispheres 473.8
Pretectal area
nTPM: 753.3
1944 Female, age 72, unknown 1024.2
2007 Male, age 72, unknown 974.7
1817 Female, age 42, unknown 947.1
1816 Male, age 51, unknown 935.9
1815 Male, age 53, unknown 834.4
2667 Female, age 75, unknown 710.6
2224 Female, age 72, unknown 642.6
2273 Male, age 74, both hemispheres 623.6
2825 Male, age 18, unknown 537.0
2316 Male, age 76, right hemisphere 534.4
2407 Male, age 75, both hemispheres 522.1
Red nucleus
nTPM: 646.4
1821 Female, age 72, unknown 856.0
2785 Male, age 18, unknown 760.5
1865 Male, age 51, unknown 694.6
2725 Female, age 75, unknown 671.3
2823 Male, age 76, right hemisphere 668.4
1954 Female, age 42, unknown 666.7
2503 Female, age 72, unknown 642.5
1904 Male, age 53, unknown 626.0
2588 Male, age 74, left hemisphere 552.0
2769 Male, age 72, unknown 543.3
2584 Male, age 75, left hemisphere 539.5
2227 Male, age 72, unknown 535.6
Substantia nigra
nTPM: 635.0
1889 Female, age 72, unknown 829.3
2241 Male, age 72, unknown 753.2
2590 Female, age 75, unknown 664.2
1941 Male, age 53, unknown 657.5
1916 Female, age 42, unknown 656.2
1851 Male, age 51, unknown 640.0
2409 Female, age 72, unknown 620.0
2583 Male, age 75, right hemisphere 585.2
2665 Male, age 74, both hemispheres 539.9
2699 Male, age 18, unknown 404.8
Superior colliculus
nTPM: 629.3
2087 Female, age 72, unknown 763.3
1913 Female, age 42, unknown 728.8
2587 Male, age 74, left hemisphere 717.7
2261 Male, age 18, unknown 688.6
1895 Male, age 76, right hemisphere 669.3
1995 Male, age 72, unknown 604.7
1796 Male, age 53, unknown 578.5
2668 Female, age 75, unknown 559.8
1839 Male, age 51, unknown 524.9
2664 Male, age 75, both hemispheres 457.6
Ventral tegmental area
nTPM: 561.8
2410 Female, age 72, unknown 647.7
2223 Female, age 72, unknown 563.6
1915 Female, age 42, unknown 549.4
2218 Male, age 76, both hemispheres 548.3
1942 Male, age 51, unknown 534.5
2021 Male, age 53, unknown 527.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1156.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1156.5
Samples: 183

Max nTPM: 2040.5
Min nTPM: 426.2
Std nTPM: 234.3
Median nTPM: 1136.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2040.5
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 1938.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1782.2
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 1740.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1724.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 1654.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1629.9
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 1613.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1596.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1547.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1510.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1481.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1455.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1452.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1447.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1442.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1441.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1421.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1415.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1409.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1407.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1404.9
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 1401.3
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 1399.0
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 1397.2
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 1397.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 1376.7
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 1368.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1365.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1355.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1355.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1354.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1351.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1348.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1343.6
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 1342.9
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 1331.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1330.8
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 1320.3
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 1318.5
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 1316.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 1307.4
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 1305.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1301.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1297.8
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 1292.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1285.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1282.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1282.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1280.0
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 1271.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1259.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1259.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1254.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1250.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1250.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1241.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1239.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1237.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1236.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1234.4
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 1227.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1221.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1216.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1210.2
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 1209.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1203.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1199.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1198.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1196.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1183.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1180.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1179.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1171.3
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 1168.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 1166.9
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 1165.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 1162.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1154.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1153.6
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 1151.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1150.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1149.1
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 1146.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1145.1
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 1144.6
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 1144.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1143.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1142.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1142.3
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 1141.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1136.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1136.0
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 1129.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1122.7
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 1121.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1121.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1120.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 1120.6
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 1117.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1111.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1110.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1104.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1104.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1103.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1102.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1099.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1097.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1096.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1096.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1095.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1094.0
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 1092.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1090.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1090.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1089.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1087.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1087.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1084.6
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 1083.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1082.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1081.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1078.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1077.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1075.2
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 1070.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1068.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1064.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1063.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1052.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1050.9
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 1047.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1045.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1039.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1033.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1028.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1020.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1017.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1017.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1015.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 1014.4
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 1005.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1005.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1003.2
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 993.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 987.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 987.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 984.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 984.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 983.5
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 977.9
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 974.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 965.0
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 964.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 958.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 958.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 956.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 955.8
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 938.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 933.8
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 929.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 924.2
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 923.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 921.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 906.8
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 897.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 895.9
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 888.7
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 878.5
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 858.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 841.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 829.4
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 829.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 805.6
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 804.9
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 801.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 748.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 666.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 661.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 655.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 606.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 464.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 426.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1158.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1158.3
FF:10158-103A5 76 years, female 1158.3

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2.8
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 2.8
Samples: 1

Max nTPM: 2.8
Min nTPM: 2.8
Sample A 2.8
Midbrain
nTPM: 0.5
Samples: 1

Max nTPM: 0.5
Min nTPM: 0.5
Sample A 0.5
Superior colliculi
nTPM: 1.0
Samples: 1

Max nTPM: 1.0
Min nTPM: 1.0
Sample A 1.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1067.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 944.2
Samples: 3

Max nTPM: 1265.3
Min nTPM: 747.5
Sample A Female 1265.3
Sample B Female 747.5
Sample C Male 819.7
Midbrain
nTPM: 1067.0
Samples: 3

Max nTPM: 1355.2
Min nTPM: 870.6
Sample B Female 870.6
Sample C Male 1355.2
Sample D Male 975.3
Periaqueductal gray
nTPM: 667.5
Samples: 3

Max nTPM: 776.0
Min nTPM: 599.6
Sample B Female 627.0
Sample C Male 776.0
Sample D Male 599.6
Superior colliculi
nTPM: 1038.8
Samples: 4

Max nTPM: 1314.7
Min nTPM: 797.5
Sample A Female 1164.5
Sample B Female 797.5
Sample C Male 1314.7
Sample D Male 878.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

611.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 611.4
Samples: 4

Max nTPM: 625.4
Min nTPM: 597.9
Sample A 613.6
Sample B 608.6
Sample C 597.9
Sample D 625.4

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

496.5
Rat sample Sample description nTPM
Midbrain
nTPM: 496.5
Samples: 4

Max nTPM: 503.8
Min nTPM: 486.3
Sample A 497.9
Sample A 498.1
Sample A 503.8
Sample A 486.3

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