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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
45.0
nTPM
HPA:
20.5
nTPM
GTEx:
45.0
nTPM
FANTOM5:
66.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA004689
Antibody HPA008285
Cholangiocytes
Medium
Not detected
Hepatocytes
Not detected
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
20.5
Female, age 60
Liver sample 21 nTPM: 22.9
Male, age 54
Liver sample 23 nTPM: 21.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 19.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 9.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 14.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 24.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 24.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 21.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 24.1
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 23.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
45.0
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 45.0
Samples: 226
Max nTPM: 111.3
Min nTPM: 23.3
Std nTPM: 11.4
Median nTPM: 42.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
111.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
85.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
81.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
81.0
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
79.4
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
71.6
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
68.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
68.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
68.2
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
67.8
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
67.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
67.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
67.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
65.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
64.6
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
62.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
62.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
62.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
60.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
60.4
GTEX-12696-0826-SM-5EGGE
60-69 years, male
60.4
GTEX-1B933-1226-SM-731DW
50-59 years, female
60.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
59.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
58.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
58.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
58.2
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
57.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
57.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
56.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
55.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
55.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
55.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
54.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
54.7
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
54.6
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
54.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
53.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
52.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
52.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
52.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
52.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
52.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
52.2
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
52.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
51.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
51.4
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
51.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
51.0
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
50.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
50.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
50.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
50.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
50.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
50.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
50.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
50.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
50.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
50.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
50.0
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
50.0
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
49.7
GTEX-14XAO-0226-SM-68728
60-69 years, female
49.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
49.2
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
48.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
48.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
48.8
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
48.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
48.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
48.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
48.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
48.2
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
48.2
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
48.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
48.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
48.0
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
47.8
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
47.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
47.8
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
47.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
47.7
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
47.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
47.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
47.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
47.1
GTEX-YECK-1926-SM-4W21H
60-69 years, male
47.1
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
47.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
46.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
46.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
46.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
46.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
46.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
45.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
45.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
45.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
45.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
44.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
44.7
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
44.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
44.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
44.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
44.2
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
43.8
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
43.7
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
43.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
43.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
43.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
43.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
43.2
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
43.1
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
43.1
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
43.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
42.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
42.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
42.7
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
42.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
42.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
42.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
42.5
GTEX-18A7A-1526-SM-72D69
50-59 years, female
42.4
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
42.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
42.1
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
42.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
42.1
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
42.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
41.9
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
41.9
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
41.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
41.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
41.6
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
41.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
41.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
41.1
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
41.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
41.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
40.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
40.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
40.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
40.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
40.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
40.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
40.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
40.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
39.9
GTEX-P78B-1326-SM-3P611
40-49 years, female
39.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
39.8
GTEX-RU72-1426-SM-46MUF
50-59 years, female
39.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
39.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
39.5
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
39.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
39.3
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
39.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
39.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
39.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
39.1
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
38.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
38.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
38.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
38.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
38.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
38.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
38.3
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
38.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
38.2
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
38.2
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
38.1
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
38.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
37.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
37.6
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
37.5
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
37.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
37.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
37.3
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
37.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
37.1
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
37.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
37.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
37.0
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
37.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
36.6
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
36.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
36.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
36.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
36.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
36.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
36.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
35.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
35.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
35.8
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
35.5
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
35.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
34.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
34.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
34.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
34.4
GTEX-1399T-0826-SM-5IFES
60-69 years, male
34.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
34.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
34.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
34.2
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
34.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
34.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
33.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
33.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
33.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
33.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
33.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
33.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
32.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
32.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
32.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
32.5
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
32.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
32.1
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
31.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
31.4
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
31.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
30.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
29.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
28.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
28.7
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
28.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
28.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
28.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
27.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
26.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
25.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
23.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
