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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cells in glomeruli:
Low
Cells in tubules:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
74.6
nTPM
HPA:
27.0
nTPM
GTEx:
74.6
nTPM
KIDNEY - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA046697
Antibody HPA061174
Cells in glomeruli
Low
Medium
Cells in tubules
High
High
KIDNEY - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
27.0
Female, age 58
Kidney sample 55 nTPM: 26.4
Cell types%
Cells in tubules:
60
Cells in glomeruli:
20
Fibroblasts:
5
Other cell types:
15
Female, age 67
Kidney sample 56 nTPM: 26
Cell types%
Cells in tubules:
70
Cells in glomeruli:
15
Fibroblasts:
10
Other cell types:
5
Female, age 55
Kidney sample 57 nTPM: 33.6
Cell types%
Cells in tubules:
80
Cells in glomeruli:
10
Fibroblasts:
5
Other cell types:
5
Male, age 46
Kidney sample 58 nTPM: 28.6
Cell types%
Cells in tubules:
60
Cells in glomeruli:
25
Fibroblasts:
5
Other cell types:
10
Female, age 57
Kidney sample 358 nTPM: 13.9
Cell types%
Cells in tubules:
60
Cells in glomeruli:
10
Fibroblasts:
10
Other cell types:
20
Male, age 78
Kidney sample 377 nTPM: 27.9
Cell types%
Cells in tubules:
65
Cells in glomeruli:
10
Fibroblasts:
5
Other cell types:
20
Male, age 73
Kidney sample 380 nTPM: 43.2
Cell types%
Cells in tubules:
60
Cells in glomeruli:
10
Fibroblasts:
10
Other cell types:
20
Female, age 59
Kidney sample 394 nTPM: 26
Cell types%
Cells in tubules:
65
Cells in glomeruli:
10
Fibroblasts:
10
Other cell types:
15
Female, age 48
Kidney sample 414 nTPM: 17.6
Cell types%
Cells in tubules:
60
Cells in glomeruli:
5
Fibroblasts:
10
Other cell types:
25
KIDNEY - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
74.6
GTEx sample id
Sample description
nTPM
Kidney - Cortex Average nTPM: 74.6
Samples: 85
Max nTPM: 111.0
Min nTPM: 42.1
Std nTPM: 16.1
Median nTPM: 73.3
GTEX-17F96-1926-SM-7MGWY
70-79 years, male
111.0
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
107.6
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
106.3
GTEX-12696-0926-SM-5FQTV
60-69 years, male
104.9
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
103.6
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
100.9
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
97.1
GTEX-QLQW-1626-SM-CMKFE
30-39 years, male
97.1
GTEX-1H3VY-1926-SM-9JGHJ
50-59 years, male
96.0
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
95.6
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
94.1
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
93.9
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
93.0
GTEX-1E2YA-1626-SM-7MGXS
50-59 years, male
90.3
GTEX-1GMR3-2426-SM-7MXV2
40-49 years, male
89.6
GTEX-T6MN-1826-SM-EXOHN
50-59 years, male
89.5
GTEX-14C39-2126-SM-664OH
40-49 years, male
89.2
GTEX-1OJC4-2326-SM-DTXA5
50-59 years, female
89.1
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
88.5
GTEX-1C6VQ-2326-SM-7IGN1
50-59 years, male
88.4
GTEX-1LG7Y-2726-SM-D5OVW
50-59 years, male
88.4
GTEX-O5YV-1226-SM-EV795
60-69 years, female
87.3
GTEX-1J1OQ-1426-SM-AHZ3P
40-49 years, female
85.9
GTEX-14C5O-2026-SM-5YYB1
60-69 years, male
85.8
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
84.5
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
84.2
GTEX-1HB9E-1826-SM-D4P33
50-59 years, male
84.1
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
83.6
GTEX-13112-2126-SM-5GCO4
50-59 years, male
83.3
GTEX-ZDXO-0226-SM-4WKH7
60-69 years, male
82.7
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
82.6
GTEX-1JMLX-1526-SM-AHZ3N
50-59 years, male
81.9
GTEX-15CHQ-2126-SM-6871M
60-69 years, male
77.9
GTEX-S33H-1426-SM-EZ6L7
30-39 years, male
77.1
GTEX-1NV8Z-2226-SM-EXOJ2
60-69 years, male
77.0
GTEX-17F97-1926-SM-7IGM4
50-59 years, male
76.6
GTEX-Y5V5-1226-SM-EYYVP
60-69 years, female
76.2
GTEX-1JMQK-1926-SM-CJI3B
60-69 years, male
76.1
GTEX-1H3NZ-2126-SM-9WPQ6
60-69 years, male
76.0
GTEX-1GF9W-1326-SM-7P8PX
60-69 years, male
74.3
GTEX-1JMPZ-1226-SM-ARU8Y
30-39 years, male
74.3
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
74.1
GTEX-1K9T9-1826-SM-CXZK2
50-59 years, female
73.3
GTEX-1KWVE-0826-SM-CXZKO
30-39 years, male
72.7
GTEX-1QP6S-1526-SM-EXUSG
40-49 years, male
72.7
GTEX-1HBPI-2026-SM-CE6RZ
50-59 years, male
71.8
GTEX-1JJ6O-2526-SM-AHZ3J
60-69 years, male
71.8
GTEX-1BAJH-1826-SM-731DA
70-79 years, male
71.6
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
71.5
GTEX-17HHY-2326-SM-7KFSR
50-59 years, male
70.8
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
70.2
GTEX-1F48J-2226-SM-7MXTN
50-59 years, female
69.4
GTEX-1HCU7-1826-SM-A9G2A
50-59 years, male
69.4
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
68.7
GTEX-1A3MW-2226-SM-73KUX
60-69 years, female
67.7
GTEX-1N2EF-1426-SM-EXUSH
60-69 years, male
66.2
GTEX-1R9PO-1626-SM-E6CPT
60-69 years, female
66.0
GTEX-1MUQO-2526-SM-E9TJN
60-69 years, male
64.6
GTEX-15DYW-2026-SM-6AJBD
60-69 years, female
64.2
GTEX-1IL2V-1826-SM-ARU7R
70-79 years, male
63.8
GTEX-1I1GP-1926-SM-CNNQU
50-59 years, male
63.5
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
63.1
GTEX-1GN1U-2126-SM-AHZ4J
50-59 years, female
62.6
GTEX-1A8FM-2026-SM-7P8RN
50-59 years, female
62.4
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
62.3
GTEX-1GTWX-1826-SM-9QEHG
60-69 years, male
61.6
GTEX-1AX8Z-2326-SM-731CR
60-69 years, male
60.2
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
59.6
GTEX-1CB4J-1926-SM-7MGX8
60-69 years, male
59.6
GTEX-ZE9C-1426-SM-4WKGM
60-69 years, male
58.2
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
58.1
GTEX-RN64-1626-SM-48FD7
50-59 years, male
57.4
GTEX-1GF9V-1926-SM-9JGHE
60-69 years, male
56.7
GTEX-1PWST-2226-SM-EVR3G
70-79 years, male
56.6
GTEX-1N2DW-1826-SM-EAZ54
50-59 years, male
55.7
GTEX-QDT8-1726-SM-EYYV6
30-39 years, female
55.0
GTEX-16MT8-1926-SM-7EPGL
60-69 years, female
54.1
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
53.4
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
52.6
GTEX-1JMQJ-1726-SM-E9U4V
50-59 years, male
51.1
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
49.0
GTEX-REY6-1826-SM-EAZAT
60-69 years, male
47.2
GTEX-14E6D-2526-SM-5YYA9
50-59 years, male
46.8
GTEX-1IKK5-0926-SM-A9G2U
60-69 years, male
45.7
GTEX-1EKGG-2226-SM-7IGOA
60-69 years, male
42.1
Show allShow less
Kidney - Medulla Average nTPM: 66.2
Samples: 4
Max nTPM: 87.3
Min nTPM: 37.0
Std nTPM: 18.4
Median nTPM: 70.3
The Human Protein Atlas project is funded
