Brain tissue expression of SOD2 in cerebellum

CEREBELLUM - Expression summary

Protein expression
Cerebellumⁱ

Cells in granular layer:	High
Cells in molecular layer:	High
Purkinje cells:	High

RNA expressionⁱ

HPA Brain:	186.0	nTPM
FANTOM5:	73.7	Scaled Tags Per Million

Macaque:	82.8	nTPM
Mouse:	34.3	nTPM
Rat:	50.8	nTPM
Pig:	39.5	nTPM

CEREBELLUM - Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample. Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes. Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based) Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

		Antibody HPA001814
Purkinje cells		High
Cells in granular layer		High
Cells in molecular layer		High

CEREBELLUM - PROTEINTALKS DB MS

Median intensity	65994

Sample

Intensity

Cerebellum_01

68338

Cerebellum_02

90220

Cerebellum_03

44138

Cerebellum_04

65993

Cerebellum_05

75479

Cerebellum_06

59347

Cerebellum_07

52692

Cerebellum_08

65527

Cerebellum_09

63174

Cerebellum_10

78700

Cerebellum_11

78913

CEREBELLUM - HPA Brain Stereo-seq

CEREBELLUM - HPA Brain RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	186.0

Sample id

Sample description

nTPM

Cerebellar cortex
nTPM: 108.4

2101	Male, age 74, right hemisphere	177.0
1768	Female, age 72, unknown	141.2
2055	Female, age 91, right hemisphere	108.7
2003	Female, age 85, right hemisphere	108.5
1788	Male, age 55, unknown	108.3
2006	Male, age 61, right hemisphere	82.2
1774	Male, age 80, left hemisphere	74.8
1769	Male, age 76, right hemisphere	66.8

Cerebellar nuclei
nTPM: 186.0

2783	Female, age 72, unknown	259.8
2882	Male, age 76, left hemisphere	190.9
1879	Male, age 55, unknown	190.4
1966	Female, age 91, left hemisphere	190.2
2177	Female, age 85, both hemispheres	189.3
2175	Male, age 61, right hemisphere	177.3
2005	Male, age 80, left hemisphere	169.7
2318	Male, age 74, left hemisphere	166.9
1871	Male, age 74, unknown	139.5

Cerebellar white matter
nTPM: 144.0

2105	Male, age 74, right hemisphere	186.3
2773	Female, age 85, right hemisphere	154.9
1931	Female, age 91, left hemisphere	145.1
1837	Male, age 76, left hemisphere	134.0
1864	Male, age 80, left hemisphere	130.8
2174	Male, age 61, right hemisphere	113.2

Flocculonodular lobe
nTPM: 111.1

2004	Male, age 61, right hemisphere	213.4
1792	Male, age 74, unknown	122.4
2176	Female, age 91, right hemisphere	105.9
1765	Male, age 55, unknown	102.1
1835	Female, age 85, right hemisphere	96.2
1771	Male, age 80, left hemisphere	73.0
1767	Male, age 76, left hemisphere	64.3

Vermis
nTPM: 117.5

1928	Female, age 72, unknown	164.9
1751	Male, age 74, right hemisphere	164.1
1766	Male, age 55, unknown	130.1
2460	Male, age 61, both hemispheres	112.4
1825	Male, age 74, unknown	109.8
2834	Male, age 80, left hemisphere	107.7
1988	Female, age 85, left hemisphere	101.5
1778	Female, age 91, left hemisphere	100.4
1770	Male, age 76, left hemisphere	66.8

CEREBELLUM - FANTOM5 CAGEⁱ

Max subtype Scaled Tags Per Millionⁱ Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.	73.7

FANTOM5 sample id

Sample description

Scaled Tags Per Million

Cerebellum
Scaled Tags Per Million: 73.7

FF:10166-103B4	76 years, female	91.5
FF:10083-102B2	22-68 years, mixed	56.0

CEREBELLUM - Macaque RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	82.8

Macaque sample

Sample description

nTPM

Cerebellum
nTPM: 82.8

Samples: 3

Max nTPM: 89.7
Min nTPM: 78.6

Sample A		80.2
Sample B		78.6
Sample C		89.7

CEREBELLUM - Pig RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	39.5

Pig sample

Sample description

nTPM

Cerebellum
nTPM: 39.5

Samples: 3

Max nTPM: 44.5
Min nTPM: 37.0

Sample B	Female	44.5
Sample C	Male	37.0
Sample D	Male	37.0

CEREBELLUM - Mouse RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	34.3

Mouse sample

Sample description

nTPM

Cerebellum
nTPM: 34.3

Samples: 4

Max nTPM: 36.5
Min nTPM: 30.3

Sample A		35.5
Sample B		36.5
Sample C		35.0
Sample D		30.3

CEREBELLUM - Rat RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	50.8

Rat sample

Sample description

nTPM

Cerebellum
nTPM: 50.8

Samples: 4

Max nTPM: 53.1
Min nTPM: 48.3

Sample A		52.0
Sample A		53.1
Sample A		48.3
Sample A		49.7