TAC1

GENERAL INFORMATION

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Gene name

TAC1

Gene description

Tachykinin, precursor 1

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (cerebral cortex, spleen)
GTEx:Tissue enhanced (hippocampus, spleen)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic and membranous expression at variable levels in most cell types.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA014429 , CAB004588
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, spleen)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (hippocampus, spleen)

Organ

Expression



GENE INFORMATION

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Gene name

TAC1 (HGNC Symbol)

Synonyms

NKNA, NPK, TAC2

Description

Tachykinin, precursor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Chromosome

7

Cytoband

q21.3

Chromosome location (bp)

97731908 - 97740472

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006128 (version 78.38)

Entrez gene

6863

UniProt

P20366 (UniProt - Evidence at protein level)

neXtProt

NX_P20366

Antibodypedia

TAC1 antibodies


PROTEIN BROWSER

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ENST00000319273
 
ENST00000346867
 
ENST00000350485
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TAC1-001 ENSP00000321106
ENST00000319273
P20366
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Show » Show » 129 15 Yes 0
TAC1-002 ENSP00000289574
ENST00000346867
P20366
Show all »
Show » Show » 114 13.3 Yes 0
TAC1-003 ENSP00000289576
ENST00000350485
P20366
Show all »
Show » Show » 111 13 Yes 0