ANO2

GENERAL INFORMATION

? »

Gene name

ANO2

Gene description

Anoctamin 2, calcium activated chloride channel

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (testis)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in several tissues types, including testis. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

? »

Data reliability
description

Presumed off target binding observed and disregarded. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA036276
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

? »

Gene name

ANO2 (HGNC Symbol)

Synonyms

C12orf3, TMEM16B

Description

Anoctamin 2, calcium activated chloride channel (HGNC Symbol)

Entrez gene summary

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

5531869 - 5946232

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000047617 (version 78.38)

Entrez gene

57101

UniProt

Q9NQ90 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQ90

Antibodypedia

ANO2 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000327087
 
ENST00000356134
 
ENST00000545860
 
ENST00000546188
 
ENST00000612575
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANO2-001 ENSP00000348453
ENST00000356134
Q9NQ90
Show all »
Show » Show » 999 113.6 No 8
ANO2-005 ENSP00000443813
ENST00000545860
F5H806
Show all »
Show » Show » 203 23.5 No 3
ANO2-201 ENSP00000314048
ENST00000327087
Q9NQ90
Show all »
Show » Show » 999 113.6 No 8
ANO2-202 ENSP00000440981
ENST00000546188
Q69YW4
Show all »
Show » 1003 113.9 No 8
ANO2-203 ENSP00000481449
ENST00000612575
Q69YW4
Show all »
Show » 86 9.4 No 0