MPP4

GENERAL INFORMATION

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Gene name

MPP4

Gene description

Membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Not detected
GTEx:Tissue enhanced (cerebellum)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Not detected

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum)

Organ

Expression



GENE INFORMATION

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Gene name

MPP4 (HGNC Symbol)

Synonyms

DLG6

Description

Membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q33.1

Chromosome location (bp)

201644870 - 201698694

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000082126 (version 78.38)

Entrez gene

58538

UniProt

Q96JB8 (UniProt - Evidence at protein level)

neXtProt

NX_Q96JB8

Antibodypedia

MPP4 antibodies


PROTEIN BROWSER

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ENST00000315506
 
ENST00000359962
 
ENST00000396886
 
ENST00000409143
 
ENST00000409474
 
ENST00000428900
 
ENST00000447335
 
ENST00000602867
 
ENST00000620095
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MPP4-001 ENSP00000387278
ENST00000409474
Q96JB8
Show all »
Show » Show » 637 72.8 No 0
MPP4-002 ENSP00000319363
ENST00000315506
Q96JB8
Show all »
Show » Show » 593 67.6 No 0
MPP4-007 ENSP00000387293
ENST00000409143
F6Q0Y6
Show all »
Show » Show » 579 66 No 0
MPP4-008 ENSP00000380095
ENST00000396886
E9PG92
Show all »
Show » Show » 562 64.3 No 0
MPP4-009 ENSP00000416781
ENST00000428900
E7ET46
Show all »
Show » Show » 613 70.1 No 0
MPP4-010 ENSP00000406160
ENST00000447335
E7EUL8
Show all »
Show » Show » 630 71.9 No 0
MPP4-012 ENSP00000473500
ENST00000602867
R4GN59
Show all »
Show » Show » 171 19.3 No 0
MPP4-201 ENSP00000353047
ENST00000359962
E7EUL8
Show all »
Show » Show » 630 71.9 No 0
MPP4-202 ENSP00000478875
ENST00000620095
Show » Show » 606 69.2 No 0