TNPO3

GENERAL INFORMATION

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Gene name

TNPO3

Gene description

Transportin 3

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA039555
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TNPO3 (HGNC Symbol)

Synonyms

IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2

Description

Transportin 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]

Chromosome

7

Cytoband

q32.1

Chromosome location (bp)

128954180 - 129055144

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000064419 (version 78.38)

Entrez gene

23534

UniProt

Q9Y5L0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5L0

Antibodypedia

TNPO3 antibodies


PROTEIN BROWSER

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ENST00000265388
 
ENST00000471166
 
ENST00000471234
 
ENST00000482320
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TNPO3-001 ENSP00000265388
ENST00000265388
Q9Y5L0
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Show » Show » 923 104.2 No 0
TNPO3-002 ENSP00000420089
ENST00000482320
E9PFH4
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Show » Show » 857 96.7 No 0
TNPO3-003 ENSP00000418646
ENST00000471234
Q9Y5L0
Show all »
Show » Show » 859 97.4 No 0
TNPO3-005 ENSP00000418267
ENST00000471166
C9J7E5
Show all »
Show » Show » 957 108 No 0