MAGED2

GENERAL INFORMATION

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Gene name

MAGED2

Gene description

Melanoma antigen family D, 2

Protein class

Cancer-related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending retesting.

Data reliability

Supportive based on 2 antibodies.
HPA031572 , HPA031573
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MAGED2 (HGNC Symbol)

Synonyms

11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386

Description

Melanoma antigen family D, 2 (HGNC Symbol)

Entrez gene summary

This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). This gene may also be involved in several types of cancer, including breast cancer and melanoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Chromosome

X

Cytoband

p11.21

Chromosome location (bp)

54807599 - 54816012

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102316 (version 78.38)

Entrez gene

10916

UniProt

Q9UNF1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNF1

Antibodypedia

MAGED2 antibodies


PROTEIN BROWSER

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ENST00000218439
 
ENST00000347546
 
ENST00000375053
 
ENST00000375058
 
ENST00000375060
 
ENST00000375068
 
ENST00000396224
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAGED2-002 ENSP00000364209
ENST00000375068
Q9UNF1
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Show » Show » 606 65 No 0
MAGED2-003 ENSP00000364198
ENST00000375058
Q9UNF1
Show all »
Show » Show » 606 65 No 0
MAGED2-004 ENSP00000336962
ENST00000347546
Q5H909
Show all »
Show » 588 63.1 No 0
MAGED2-005 ENSP00000364200
ENST00000375060
Q5H907
Show all »
Show » 521 55.8 No 0
MAGED2-201 ENSP00000218439
ENST00000218439
Q9UNF1
Show all »
Show » Show » 606 65 No 0
MAGED2-202 ENSP00000364193
ENST00000375053
Q9UNF1
Show all »
Show » Show » 606 65 No 0
MAGED2-203 ENSP00000379526
ENST00000396224
Q9UNF1
Show all »
Show » Show » 606 65 No 0