ENO2

GENERAL INFORMATION

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Gene name

ENO2

Gene description

Enolase 2 (gamma, neuronal)

Protein class

Cancer-related genes
Candidate cardiovascular disease genes
Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Distinct cytoplasmic expression in CNS, peripheral nerves and pancreatic islets. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 2 antibodies.
CAB000063 , CAB073539
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ENO2

Synonyms

Description

Enolase 2 (gamma, neuronal) (HGNC Symbol)

Entrez gene summary

This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

6913745 - 6923698

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111674 (version 78.38)

Entrez gene

2026

UniProt

P09104 (UniProt - Evidence at protein level)

neXtProt

NX_P09104

Antibodypedia

ENO2 antibodies


PROTEIN BROWSER

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ENST00000229277
 
ENST00000535366
 
ENST00000537688
 
ENST00000538763
 
ENST00000541477
 
ENST00000543975
 
ENST00000545045
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ENO2-001 ENSP00000438873
ENST00000541477
P09104
Show all »
Show » Show » 434 47.3 No 0
ENO2-002 ENSP00000437402
ENST00000535366
P09104
Show all »
Show » Show » 434 47.3 No 0
ENO2-003 ENSP00000441490
ENST00000538763
P09104
Show all »
Show » Show » 391 42.7 No 0
ENO2-004 ENSP00000438062
ENST00000545045
F5H0C8
Show all »
Show » Show » 315 34.8 No 0
ENO2-010 ENSP00000476112
ENST00000543975
Show » Show » 86 9.4 No 0
ENO2-013 ENSP00000445788
ENST00000537688
F5H1C3
Show all »
Show » Show » 103 11.2 No 0
ENO2-201 ENSP00000229277
ENST00000229277
P09104
Show all »
Show » Show » 434 47.3 No 0