CCNB3

GENERAL INFORMATION

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Gene name

CCNB3

Gene description

Cyclin B3

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Nuclear and cytoplasmic expression in seminiferous ducts in testis.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Supportive based on 1 antibody.
HPA000496
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

CCNB3

Synonyms

Description

Cyclin B3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Chromosome

X

Cytoband

p11.22

Chromosome location (bp)

50202713 - 50351910

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147082 (version 78.38)

Entrez gene

85417

UniProt

Q8WWL7 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WWL7

Antibodypedia

CCNB3 antibodies


PROTEIN BROWSER

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ENST00000276014
 
ENST00000348603
 
ENST00000376038
 
ENST00000376042
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCNB3-001 ENSP00000365210
ENST00000376042
Q8WWL7
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Show » Show » 1395 157.9 No 0
CCNB3-002 ENSP00000365206
ENST00000376038
Q8WWL7
Show all »
Show » Show » 291 33.3 No 0
CCNB3-201 ENSP00000276014
ENST00000276014
Q8WWL7
Show all »
Show » Show » 1395 157.9 No 0
CCNB3-202 ENSP00000338682
ENST00000348603
Q8WWL7
Show all »
Show » Show » 291 33.3 No 0