FZD1

GENERAL INFORMATION

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Gene name

FZD1

Gene description

Frizzled class receptor 1

Protein class

Cancer-related genes
G-protein coupled receptors
Plasma proteins
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues displayed moderate cytoplasmic staining. Hepatocytes, placental trophoblasts and cells in bone marrow were strongly stained.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
CAB013008
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

FZD1 (HGNC Symbol)

Synonyms

DKFZp564G072

Description

Frizzled class receptor 1 (HGNC Symbol)

Entrez gene summary

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q21.13

Chromosome location (bp)

91264364 - 91271326

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000157240 (version 78.38)

Entrez gene

8321

UniProt

Q9UP38 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UP38

Antibodypedia

FZD1 antibodies


PROTEIN BROWSER

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ENST00000287934
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FZD1-001 ENSP00000287934
ENST00000287934
Q9UP38
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