ATP13A2

GENERAL INFORMATION

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Gene name

ATP13A2

Gene description

ATPase type 13A2

Protein class

Disease related genes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

11
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression, most abundant in glandular cells of gastrointestinal tract and neuronal cells of the central nervous system.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 4 antibodies.
HPA050910 , HPA054717 , CAB037038 , CAB037111
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ATP13A2 (HGNC Symbol)

Synonyms

CLN12, HSA9947, PARK9

Description

ATPase type 13A2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson disease 9. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2008]

Chromosome

1

Cytoband

p36.13

Chromosome location (bp)

16985958 - 17011928

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159363 (version 78.38)

Entrez gene

23400

UniProt

Q9NQ11 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQ11

Antibodypedia

ATP13A2 antibodies


PROTEIN BROWSER

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ENST00000326735
 
ENST00000341676
 
ENST00000452699
 
ENST00000502418
 
ENST00000503552
 
ENST00000506174
 
ENST00000508222
 
ENST00000509619
 
ENST00000510069
 
ENST00000511957
 
ENST00000617114
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP13A2-001 ENSP00000327214
ENST00000326735
Q9NQ11
Show all »
Show » Show » 1180 128.8 No >9
ATP13A2-002 ENSP00000341115
ENST00000341676
Q9NQ11
Show all »
Show » Show » 1158 126 No 9
ATP13A2-005 ENSP00000413307
ENST00000452699
Q9NQ11
Show all »
Show » Show » 1175 128.3 No >9
ATP13A2-007 ENSP00000423065
ENST00000502418
H0Y953
Show all »
Show » Show » 398 42.6 No 4
ATP13A2-008 ENSP00000422227
ENST00000508222
Show » 188 21.5 No 1
ATP13A2-009 ENSP00000424313
ENST00000510069
Show » Show » 321 36 No 3
ATP13A2-010 ENSP00000422668
ENST00000509619
Show » Show » 191 21.3 No 1
ATP13A2-011 ENSP00000427241
ENST00000511957
H0YAI7
Show all »
Show » Show » 190 21.6 No 1
ATP13A2-012 ENSP00000424393
ENST00000506174
H0Y9K4
Show all »
Show » Show » 191 20.7 No 2
ATP13A2-014 ENSP00000421126
ENST00000503552
H0Y8I1
Show all »
Show » Show » 258 28.1 No 0
ATP13A2-201 ENSP00000478781
ENST00000617114
Show » Show » 228 24.5 No 2