ASB11

GENERAL INFORMATION

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Gene name

ASB11

Gene description

Ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (heart muscle, skeletal muscle)
GTEx:Group enriched (heart muscle, skeletal muscle)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in a selected group of tissues, most abundant in skeletal muscle. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA000238
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Lung

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (heart muscle, skeletal muscle)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (heart muscle, skeletal muscle)

Organ

Expression



GENE INFORMATION

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Gene name

ASB11 (HGNC Symbol)

Synonyms

DKFZp779E2460

Description

Ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Chromosome

X

Cytoband

p22.2

Chromosome location (bp)

15281697 - 15315656

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165192 (version 78.38)

Entrez gene

140456

UniProt

Q8WXH4 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WXH4

Antibodypedia

ASB11 antibodies


PROTEIN BROWSER

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ENST00000344384
 
ENST00000380470
 
ENST00000480796
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ASB11-001 ENSP00000417914
ENST00000480796
Q8WXH4
Show all »
Show » Show » 323 35.4 No 1
ASB11-003 ENSP00000343408
ENST00000344384
Q8WXH4
Show all »
Show » Show » 302 33 No 0
ASB11-004 ENSP00000369837
ENST00000380470
Q8WXH4
Show all »
Show » Show » 306 33.5 No 1