EMB

GENERAL INFORMATION

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Gene name

EMB

Gene description

Embigin

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in a selected group of tissues, most abundant in bone marrow. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA017740
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Seminal vesicle



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

EMB (HGNC Symbol)

Synonyms

MGC71745

Description

Embigin (HGNC Symbol)

Entrez gene summary

This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]

Chromosome

5

Cytoband

q11.1

Chromosome location (bp)

50396192 - 50443248

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170571 (version 78.38)

Entrez gene

133418

UniProt

Q6PCB8 (UniProt - Evidence at protein level)

neXtProt

NX_Q6PCB8

Antibodypedia

EMB antibodies


PROTEIN BROWSER

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ENST00000303221
 
ENST00000508934
 
ENST00000514111
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EMB-001 ENSP00000302289
ENST00000303221
Q6PCB8
Show all »
Show » Show » 327 36.9 Yes 1
EMB-003 ENSP00000426404
ENST00000514111
Q6PCB8
Show all »
Show » Show » 277 31.6 No 1
EMB-005 ENSP00000425215
ENST00000508934
D6RDX7
Show all »
Show » Show » 273 30.9 Yes 1