SLC25A10

GENERAL INFORMATION

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Gene name

SLC25A10

Gene description

Solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10

Protein class

Mitochondrial proteins
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression with a granular pattern.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Data reliability

Supportive based on 1 antibody.
HPA023048
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

SLC25A10 (HGNC Symbol)

Synonyms

DIC

Description

Solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

81712236 - 81721016

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183048 (version 78.38)

Entrez gene

1468

UniProt

Q9UBX3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UBX3

Antibodypedia

SLC25A10 antibodies


PROTEIN BROWSER

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ENST00000331531
 
ENST00000350690
 
ENST00000545862
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC25A10-001 ENSP00000328403
ENST00000331531
Q9UBX3
Show all »
Show » Show » 296 32.1 No 3
SLC25A10-002 ENSP00000345580
ENST00000350690
Q9UBX3
Show all »
Show » Show » 287 31.3 No 0
SLC25A10-201 ENSP00000446242
ENST00000545862
Show » Show » 406 43.6 No 0