TUBA8

GENERAL INFORMATION

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Gene name

TUBA8

Gene description

Tubulin, alpha 8

Protein class

Disease related genes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Tissue enhanced (cerebellum)

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation. Caution, targets protein from more than one gene.

Data reliability

Uncertain based on 3 antibodies.
HPA043684 , HPA063394 , CAB046031
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum)

Organ

Expression



GENE INFORMATION

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Gene name

TUBA8 (HGNC Symbol)

Synonyms

TUBAL2

Description

Tubulin, alpha 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

18110331 - 18146554

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183785 (version 78.38)

Entrez gene

51807

UniProt

Q9NY65 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NY65

Antibodypedia

TUBA8 antibodies


PROTEIN BROWSER

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ENST00000316027
 
ENST00000330423
 
ENST00000416740
 
ENST00000426208
 
ENST00000608634
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TUBA8-001 ENSP00000333326
ENST00000330423
Q9NY65
Show all »
Show » Show » 449 50.1 No 0
TUBA8-002 ENSP00000318575
ENST00000316027
Q9NY65
Show all »
Show » Show » 383 43 No 0
TUBA8-003 ENSP00000412646
ENST00000416740
C9J2C0
Show all »
Show » Show » 467 52 No 0
TUBA8-004 ENSP00000407624
ENST00000426208
C9K0S6
Show all »
Show » Show » 47 5.3 No 0
TUBA8-005 ENSP00000477306
ENST00000608634
Show » Show » 275 31 No 1