ADARB1

GENERAL INFORMATION

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Gene name

ADARB1

Gene description

Adenosine deaminase, RNA-specific, B1

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Sub cellular location is contradicted by external data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA018277
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ADARB1 (HGNC Symbol)

Synonyms

ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1

Description

Adenosine deaminase, RNA-specific, B1 (HGNC Symbol)

Entrez gene summary

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.3

Chromosome location (bp)

45073853 - 45226560

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197381 (version 78.38)

Entrez gene

104

UniProt

P78563 (UniProt - Evidence at protein level)

neXtProt

NX_P78563

Antibodypedia

ADARB1 antibodies


PROTEIN BROWSER

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ENST00000348831
 
ENST00000360697
 
ENST00000389863
 
ENST00000437626
 
ENST00000449478
 
ENST00000611195
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADARB1-004 ENSP00000353920
ENST00000360697
P78563
Show all »
Show » Show » 741 80.8 No 0
ADARB1-005 ENSP00000374513
ENST00000389863
P78563
Show all »
Show » Show » 714 77.8 No 0
ADARB1-008 ENSP00000387480
ENST00000449478
Show » 141 15.1 No 0
ADARB1-011 ENSP00000015877
ENST00000348831
P78563
Show all »
Show » Show » 701 76.6 No 0
ADARB1-201 ENSP00000414600
ENST00000437626
P78563
Show all »
Show » Show » 741 80.8 No 0
ADARB1-202 ENSP00000478160
ENST00000611195
Q8TCX7
Show all »
Show » 52 6 No 0