THE HUMAN PROTEIN ATLAS BLOG

Proteomic profiling of sarcoidosis patients

2016-06-14   |   0 Comments
Antibody Suspension Bead Array Sandwich immunoassays

Levels of FN1 and CCL2 in BAL fluid.

In a very recent study, published in Respiratory Research, researchers from the Human Protein Atlas and Karolinska Institutet performed protein profiling of broncho-alveolar lavage (BAL)-fluid and serum using an antibody suspension bead array technology with the aim to find proteins associated to sarcoidosis.

Sarcoidosis is a granulomatous systemic inflammatory disease in which more than 90 % of all patients develop pulmonary manifestations. Several gene associations have previously been described, but established and clinically useful biomarkers are still absent...Read more


On childhood asthma and protein profiles in plasma

2016-05-24   |   0 Comments
Antibody Suspension Bead Array Asthma Human Protein Atlas Plasma

Protein levels of CCL5, HPGDS and NPSR1 in plasma

In a recent publication in European Journal of Allergy and Clinical Immunology, researchers use an affinity proteomics approach to analyze plasma profiles of a 362 proteins in 154 children with persistent or intermittent asthma and controls. To this end, antibody suspension bead arrays developed within the Human Protein Atlas was used.

Asthma is a common chronic childhood disease with many different phenotypes that need to be identified. Asthma affects approximately 300 million people worldwide and is characterized by bronchial hyperresponsiveness and reversible expiratory airflow limitation...Read more