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The secretome and membrane proteome

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Secreted and membrane-bound proteins are important for physiological processes and are potential drug targets as they are easily accessible in the extracellular space and provide a gateway to the intracellular environment. About 3,000 protein-coding genes are predicted members of the secretome; examples of secreted proteins are cytokines, coagulation factors, hormones, and growth factors. Important members of the membrane proteome, consisting of about 5,500 genes encoding predicted membrane-bound proteins, are ion channels of molecular transporters, enzymes, receptors, and anchors for other proteins.

A majority of the human genes encode several splice variants...Read more


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WIRM XIV

March 4, 2020 - March 7, 2020

Mathias Uhlén, Petter Brodin and Fredrik Edfors will participate in the World Immune Regulation Meeting XIV in Davos.

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FEBS Practical and Lecture Course

June 21, 2020 - June 26, 2020

FEBS Practical and Lecture Course - A summer school aimed at graduate students, post-docs, and young independent investigators who want to learn about new techniques to explore the proteins encoded by the human genome.

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