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The secretome and membrane proteome

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Secreted and membrane-bound proteins are important for physiological processes and are potential drug targets as they are easily accessible in the extracellular space and provide a gateway to the intracellular environment. About 3,000 protein-coding genes are predicted members of the secretome; examples of secreted proteins are cytokines, coagulation factors, hormones, and growth factors. Important members of the membrane proteome, consisting of about 5,500 genes encoding predicted membrane-bound proteins, are ion channels of molecular transporters, enzymes, receptors, and anchors for other proteins.

A majority of the human genes encode several splice variants...Read more


Upcoming Events


XII EuPA Congress

June 16, 2018 - June 20, 2018

On Tuesday June 19, Jochen Schwenk will present "An update on the Human Plasma Proteome" at the XII EuPA Congress - Translating genomes into biological functions.