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The secretome and membrane proteome

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Secreted and membrane-bound proteins are important for physiological processes and are potential drug targets as they are easily accessible in the extracellular space and provide a gateway to the intracellular environment. About 3,000 protein-coding genes are predicted members of the secretome; examples of secreted proteins are cytokines, coagulation factors, hormones, and growth factors. Important members of the membrane proteome, consisting of about 5,500 genes encoding predicted membrane-bound proteins, are ion channels of molecular transporters, enzymes, receptors, and anchors for other proteins.

A majority of the human genes encode several splice variants...Read more


Upcoming Events


Proteomics in Cell Biology and Disease Mechanisms

February 28, 2018 - March 2, 2018

The Wellcome Genome Campus organizes the conference Proteomics in Cell Biology and Disease Mechanisms where Dr. Emma Lundberg will present "Dissecting the spatiotemporal subcellular distribution of the human proteome". Her talk is scheduled on March 2. Draft programme

US HUPO

March 11, 2018 - March 14, 2018

The title of 2018 year's US HUPO conference is "Technology accelerating discovery". Dr. Emma Lundberg will hold the closing plenary session on March 14. Programme