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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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181.076
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:51.9 nTPM
HPA:51.9 nTPM
FANTOM5:124.0 Scaled Tags Per Million
Pig:59.2 nTPM
Mouse:64.7 nTPM
Allen mouse:3.1 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA024470
Pons mean intensity 181.076
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

Read more
FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 50.899
Parabrachial nucleus 54.678
Principle sensory trigeminal nucleus 36.238
Locus coeruleus 181.076
Pontine nucleus 43.367
Vestibular nucleus 109.420
Pontine reticular nucleus, oral 30.080
Lateral lemniscus 59.143
Superior paraolivary nucleus 41.010

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 51.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 37.7
1984 Male, age 76, both hemispheres 40.5
2301 Female, age 85, both hemispheres 37.5
2090 Male, age 80, both hemispheres 36.9
2188 Female, age 91, both hemispheres 35.9
Area postrema
nTPM: 51.9
2799 Male, age 61, both hemispheres 60.8
2054 Male, age 76, both hemispheres 47.8
2306 Male, age 80, both hemispheres 47.1
Cuneate nuclei
nTPM: 40.5
2131 Male, age 76, both hemispheres 43.4
2376 Male, age 61, both hemispheres 42.7
2381 Male, age 80, both hemispheres 35.4
Dorsal cochlear nucleus
nTPM: 37.7
2370 Male, age 61, both hemispheres 40.9
2058 Male, age 76, both hemispheres 40.1
2378 Male, age 80, both hemispheres 38.7
2187 Female, age 91, both hemispheres 35.7
2802 Male, age 74, right hemisphere 33.2
Dorsal medullary reticular nucleus
nTPM: 38.5
2373 Male, age 61, both hemispheres 40.0
2088 Male, age 76, both hemispheres 39.4
2040 Female, age 85, both hemispheres 36.3
Dorsal motor vagal complex
nTPM: 40.5
2797 Male, age 61, both hemispheres 47.8
2185 Male, age 76, both hemispheres 46.1
2000 Male, age 74, unknown 44.0
2133 Female, age 91, both hemispheres 39.4
2844 Male, age 55, unknown 38.0
2643 Male, age 74, both hemispheres 37.6
2813 Female, age 72, unknown 36.7
2807 Female, age 85, both hemispheres 34.6
Dorsal tegmental nucleus
nTPM: 41.6
2358 Male, age 61, both hemispheres 42.9
1936 Male, age 76, left hemisphere 42.7
2083 Male, age 80, both hemispheres 41.6
2326 Male, age 74, both hemispheres 39.3
Dorsolateral tegmental area
nTPM: 41.8
2337 Male, age 61, both hemispheres 44.6
2360 Male, age 74, both hemispheres 44.0
2751 Female, age 85, both hemispheres 41.9
2654 Male, age 80, both hemispheres 41.7
2141 Male, age 76, both hemispheres 36.8
Gigantocellular reticular nuclei, medullary
nTPM: 38.4
2314 Male, age 61, both hemispheres 46.2
1876 Female, age 85, both hemispheres 40.7
2387 Female, age 91, both hemispheres 38.4
2022 Male, age 76, right hemisphere 35.9
2462 Male, age 74, both hemispheres 35.3
2310 Male, age 80, both hemispheres 33.9
Gigantocellular reticular nuclei, pars
nTPM: 36.4
2084 Female, age 85, both hemispheres 40.2
2336 Male, age 61, both hemispheres 38.0
2706 Male, age 80, both hemispheres 35.1
2168 Male, age 76, both hemispheres 34.9
2330 Male, age 80, both hemispheres 34.0
Inferior olive
nTPM: 45.1
2379 Male, age 80, both hemispheres 46.5
2178 Male, age 61, both hemispheres 46.3
2563 Male, age 74, both hemispheres 45.6
2085 Female, age 85, both hemispheres 44.5
2628 Female, age 91, both hemispheres 42.5
Kolliker-Fuse nucleus
nTPM: 44.9
2315 Male, age 76, right hemisphere 52.2
2163 Male, age 80, both hemispheres 48.1
2793 Female, age 91, left hemisphere 34.3
Lateral lemniscal nuclei
nTPM: 35.8
2746 Female, age 85, left hemisphere 40.3
2453 Male, age 74, right hemisphere 36.0
2169 Male, age 76, both hemispheres 35.0
2320 Female, age 91, left hemisphere 34.7
2036 Male, age 80, both hemispheres 33.0
Lateral medullary reticular nucleus
nTPM: 42.8
2852 Male, age 80, both hemispheres 45.4
2305 Male, age 74, both hemispheres 44.4
2804 Female, age 91, both hemispheres 43.4
2190 Female, age 85, both hemispheres 42.2
2044 Male, age 76, both hemispheres 40.9
2374 Male, age 61, both hemispheres 40.6
Lateral parabrachial nucleus
nTPM: 41.3
2792 Male, age 76, both hemispheres 43.9
2139 Female, age 85, right hemisphere 40.7
2013 Male, age 80, both hemispheres 40.5
2790 Male, age 61, both hemispheres 40.0
Lateral vestibular nucleus
nTPM: 43.6
2184 Male, age 76, both hemispheres 49.0
2311 Male, age 80, both hemispheres 38.2
Locus coeruleus
nTPM: 36.6
2317 Female, age 72, unknown 39.3
2123 Female, age 91, both hemispheres 39.1
1980 Male, age 76, both hemispheres 38.6
2788 Male, age 74, unknown 36.3
2162 Male, age 80, both hemispheres 36.0
2014 Male, age 55, unknown 35.5
2720 Male, age 74, both hemispheres 31.3
Medial olivary nucleus
nTPM: 46.6
1943 Male, age 61, both hemispheres 48.8
2138 Female, age 91, both hemispheres 47.6
1962 Male, age 76, both hemispheres 47.4
2851 Male, age 80, both hemispheres 42.7
Medial parabrachial nucleus
nTPM: 39.1
2156 Male, age 61, both hemispheres 41.2
2463 Female, age 85, right hemisphere 41.0
2786 Male, age 76, both hemispheres 39.1
2170 Female, age 91, both hemispheres 39.0
2854 Male, age 80, both hemispheres 35.4
Medial periolivary nuclei
nTPM: 36.2
2081 Male, age 80, both hemispheres 38.5
2791 Male, age 74, right hemisphere 36.7
2458 Female, age 91, both hemispheres 36.6
2171 Female, age 85, both hemispheres 35.2
2063 Male, age 76, both hemispheres 34.0
Medial vestibular nucleus
nTPM: 40.3
2134 Male, age 76, both hemispheres 47.5
2624 Male, age 61, both hemispheres 42.1
2093 Male, age 80, both hemispheres 38.8
2801 Male, age 74, both hemispheres 38.1
2743 Female, age 85, both hemispheres 38.0
2803 Female, age 91, both hemispheres 37.4
Motor facial nucleus
nTPM: 36.5
2795 Female, age 91, both hemispheres 42.4
2126 Male, age 61, both hemispheres 39.4
2365 Male, age 74, right hemisphere 36.8
2062 Male, age 76, both hemispheres 34.1
2697 Female, age 85, both hemispheres 34.0
2327 Male, age 80, both hemispheres 32.5
Motor hypoglossal nucleus
nTPM: 40.4
2461 Male, age 61, both hemispheres 48.2
2277 Male, age 76, both hemispheres 41.9
2125 Female, age 91, both hemispheres 41.3
2182 Male, age 80, both hemispheres 36.6
2132 Female, age 85, both hemispheres 33.8
Motor trigeminal nucleus
nTPM: 37.0
2309 Male, age 76, both hemispheres 39.8
2335 Male, age 61, both hemispheres 38.6
2079 Male, age 80, both hemispheres 36.2
2321 Female, age 91, both hemispheres 35.3
2560 Male, age 74, both hemispheres 35.0
Nuclei of the trapezoid body
nTPM: 37.6
2159 Male, age 61, both hemispheres 40.8
2368 Female, age 91, both hemispheres 40.1
2735 Female, age 85, both hemispheres 36.7
1983 Male, age 76, both hemispheres 35.7
2166 Male, age 80, both hemispheres 34.5
Nucleus ambiguus
nTPM: 43.5
2071 Male, age 76, both hemispheres 47.3
2096 Female, age 85, both hemispheres 39.8
Nucleus cuneatus
nTPM: 42.7
2100 Male, age 76, both hemispheres 45.5
2562 Male, age 61, both hemispheres 43.7
2808 Female, age 85, both hemispheres 43.4
2380 Male, age 80, both hemispheres 42.5
2564 Male, age 74, both hemispheres 41.9
2805 Female, age 91, both hemispheres 39.2
Nucleus gracilis
nTPM: 39.4
2627 Male, age 74, both hemispheres 41.1
2299 Female, age 85, both hemispheres 39.3
2382 Male, age 80, both hemispheres 37.9
Nucleus raphe magnus
nTPM: 36.3
2051 Male, age 76, both hemispheres 39.9
2160 Male, age 61, both hemispheres 37.6
2455 Male, age 74, both hemispheres 36.1
2459 Female, age 91, both hemispheres 36.0
2328 Male, age 80, both hemispheres 34.8
2172 Female, age 85, both hemispheres 33.3
Nucleus raphe obscurus
nTPM: 43.6
2142 Male, age 76, midline 53.2
2800 Male, age 61, midline 40.3
2845 Female, age 85, midline 37.4
Nucleus raphe pallidus
nTPM: 47.1
1924 Male, age 61, midline 50.7
2145 Male, age 76, midline 50.0
2183 Male, age 80, midline 40.7
Nucleus tractus solitarii
nTPM: 39.5
2191 Female, age 85, both hemispheres 42.9
2144 Female, age 91, right hemisphere 40.5
2656 Male, age 76, both hemispheres 38.9
2307 Male, age 80, both hemispheres 35.6
Paramedian reticular nucleus
nTPM: 38.8
2057 Male, age 80, both hemispheres 41.9
2313 Male, age 61, both hemispheres 39.4
2052 Male, age 76, both hemispheres 38.5
2050 Female, age 85, both hemispheres 35.3
Parvicellular reticular nuclei
nTPM: 39.3
2119 Male, age 80, both hemispheres 44.7
2095 Male, age 76, both hemispheres 39.7
2558 Male, age 74, both hemispheres 33.6
Parvicellular reticular nuclei, medullary
nTPM: 37.3
2091 Female, age 85, both hemispheres 41.4
2189 Female, age 91, both hemispheres 37.8
2181 Male, age 80, left hemisphere 32.7
Peritrigeminal nucleus
nTPM: 42.7
2136 Male, age 76, both hemispheres 44.4
2067 Female, age 85, both hemispheres 42.8
2179 Male, age 61, both hemispheres 40.9
Pontine nuclei
nTPM: 38.2
1863 Male, age 55, unknown 43.0
2109 Female, age 72, unknown 41.6
2115 Male, age 80, left hemisphere 41.0
2727 Male, age 61, right hemisphere 39.6
1968 Male, age 76, left hemisphere 36.0
2454 Male, age 74, left hemisphere 35.4
2787 Female, age 85, both hemispheres 34.9
2319 Female, age 91, both hemispheres 34.3
Pontine raphe nucleus
nTPM: 34.7
2853 Male, age 76, midline 36.5
2122 Female, age 85, midline 32.8
Posteroventral cochlear nucleus
nTPM: 38.8
2341 Male, age 80, both hemispheres 40.5
2371 Male, age 61, both hemispheres 39.5
2070 Male, age 76, both hemispheres 39.3
2135 Female, age 91, both hemispheres 38.3
2752 Female, age 85, both hemispheres 36.6
Prepositus hypoglossal nucleus
nTPM: 40.7
2855 Female, age 85, right hemisphere 42.0
2086 Male, age 80, both hemispheres 39.3
Principal sensory trigeminal nucleus
nTPM: 39.0
2324 Male, age 76, both hemispheres 47.9
2158 Male, age 61, both hemispheres 38.7
2367 Female, age 91, left hemisphere 35.1
2008 Male, age 80, left hemisphere 34.5
Reticular pontine nucleus, caudal
nTPM: 37.3
2092 Male, age 76, both hemispheres 39.5
2457 Female, age 91, both hemispheres 38.8
2559 Male, age 74, both hemispheres 35.6
2332 Male, age 80, right hemisphere 35.2
Reticular pontine nucleus, oral
nTPM: 37.6
1939 Male, age 80, both hemispheres 43.0
2167 Male, age 76, both hemispheres 39.0
2012 Female, age 85, both hemispheres 37.5
2366 Female, age 91, both hemispheres 36.1
2361 Male, age 74, both hemispheres 32.6
Reticulotegmental nucleus
nTPM: 36.2
2333 Male, age 80, both hemispheres 38.7
2322 Female, age 91, both hemispheres 37.2
2452 Male, age 74, both hemispheres 35.1
2325 Male, age 76, both hemispheres 34.0
Spinal trigeminal nucleus, caudal
nTPM: 39.4
2447 Male, age 76, both hemispheres 42.8
2390 Female, age 91, both hemispheres 40.1
2312 Male, age 61, both hemispheres 39.6
2308 Male, age 80, both hemispheres 38.3
2642 Male, age 74, both hemispheres 36.0
Spinal trigeminal nucleus, interpolar
nTPM: 42.2
2625 Male, age 61, both hemispheres 63.7
2033 Male, age 80, both hemispheres 39.9
2066 Male, age 76, right hemisphere 38.3
2386 Female, age 85, both hemispheres 34.8
2389 Female, age 91, both hemispheres 34.1
Spinal trigeminal nucleus, oral
nTPM: 40.2
2737 Female, age 85, both hemispheres 43.0
2164 Male, age 80, both hemispheres 40.8
1978 Male, age 76, both hemispheres 36.9
Spinal vestibular nucleus
nTPM: 37.2
2748 Male, age 76, both hemispheres 40.1
2780 Male, age 80, both hemispheres 37.8
2796 Male, age 61, both hemispheres 37.8
2186 Female, age 91, both hemispheres 36.9
2384 Male, age 74, both hemispheres 35.8
2806 Female, age 85, both hemispheres 34.5
Subcoeruleus area
nTPM: 36.9
2369 Female, age 85, left hemisphere 41.4
1958 Male, age 80, both hemispheres 37.6
2089 Male, age 76, left hemisphere 36.7
2451 Male, age 74, both hemispheres 34.9
2323 Female, age 91, left hemisphere 34.1
Superior olive
nTPM: 35.6
2364 Male, age 74, right hemisphere 38.6
2020 Male, age 76, both hemispheres 37.3
2329 Male, age 80, right hemisphere 34.5
1875 Female, age 85, both hemispheres 34.0
2561 Female, age 91, both hemispheres 33.8
Superior vestibular nucleus
nTPM: 43.2
2061 Male, age 76, both hemispheres 43.9
2383 Male, age 74, both hemispheres 43.9
2015 Male, age 80, both hemispheres 41.8
Ventral medullary reticular nucleus
nTPM: 42.3
2372 Male, age 61, both hemispheres 42.9
2060 Male, age 76, both hemispheres 41.6
Ventral periolivary nuclei
nTPM: 35.3
2130 Female, age 85, both hemispheres 37.2
2165 Male, age 80, both hemispheres 36.4
2023 Male, age 76, both hemispheres 35.6
2794 Female, age 91, left hemisphere 31.9
Ventrolateral medulla, A1-C1 cell groups
nTPM: 40.7
1986 Male, age 76, both hemispheres 43.6
2302 Female, age 91, both hemispheres 42.3
2180 Male, age 61, both hemispheres 40.0
2741 Female, age 85, both hemispheres 39.9
2118 Male, age 80, both hemispheres 37.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 37.6
2359 Male, age 61, both hemispheres 39.0
2840 Female, age 85, both hemispheres 38.8
2456 Female, age 91, both hemispheres 37.9
2449 Male, age 74, both hemispheres 36.9
2161 Male, age 80, both hemispheres 36.8
1959 Male, age 76, both hemispheres 36.3

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 124.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 124.0
FF:10182-103D2 60 years, female 125.0
FF:10165-103B3 76 years, female 123.1
Medulla oblongata
Scaled Tags Per Million: 116.3
FF:10155-103A2 76 years, female 141.8
FF:10038-101F2 18-64 years, mixed 103.8
FF:10174-103C3 60 years, female 103.4
Pons
Scaled Tags Per Million: 71.0
FF:10033-101E6 18-54 years, mixed 71.0

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 59.2
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 59.2
Samples: 4

Max nTPM: 65.9
Min nTPM: 51.9
Sample A Female 57.8
Sample B Female 51.9
Sample C Male 61.2
Sample D Male 65.9
Pons
nTPM: 45.1
Samples: 4

Max nTPM: 56.3
Min nTPM: 33.5
Sample A Female 46.6
Sample B Female 33.5
Sample C Male 43.8
Sample D Male 56.3

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 64.7
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 64.7
Samples: 4

Max nTPM: 69.1
Min nTPM: 60.5
Sample A Male 60.5
Sample B Male 65.3
Sample C Female 64.0
Sample D Female 69.1

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 3.1
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 3.1
73817430 Antisense, RP_051101_01_A05, Mouse strain C57BL/6J (56 days, male) 3.5
77798987 Antisense, RP_070212_03_A11, Mouse strain C57BL/6J (56 days, male) 3.1
69540345 Antisense, RP_050426_01_E10, Mouse strain C57BL/6J (56 days, male) 2.6
Pons
Expression energy: 2.1
73817430 Antisense, RP_051101_01_A05, Mouse strain C57BL/6J (56 days, male) 2.6
77798987 Antisense, RP_070212_03_A11, Mouse strain C57BL/6J (56 days, male) 2.2
69540345 Antisense, RP_050426_01_E10, Mouse strain C57BL/6J (56 days, male) 1.5

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