The human protein atlas blog


Prognostic genes in pancreatic cancer

2017-11-17
Cancer Immunohistochemistry Pancreatic cancer Pathology Atlas TCGA

Figure 1. Immunohistochemical staining of MUC1 shows differential expression pattern in samples from pancreatic cancer patients.

As part of the release of the Pathology Atlas, the Human Protein Atlas Blog will present brief and informative summaries of all cancers, and highlight genes with prognostic association in the different cancer forms. If you missed the latest Pathology Atlas blog post about prognostic genes in lung cancer, click here.

Next in our series is Pancreatic cancer, a relatively rare cancer associated with very poor prognosis. The vast majority of tumors originate from ductal cells and a small fraction are endocrine tumors...Read more


Wellness Profiling program presented at the EMBL organised symposium - From Single to Multi-omics

2017-11-10
Human Protein Atlas omics Wellness project

On Nov 13, Dr Linn Fagerberg has presented a talk entitled "Integrative omics profiling within the Swedish SCAPIS SciLifeLab (S3) Wellness Profiling program" at the EMBO|EMBL symposia "From Single to Multi-omics: Applications and Challenges in Data Integration" in Heidelberg, Germany. The talk focused on the integration of data retrieved from the analysis of biological samples collected within the SCAPIS project using different technological platforms. On the same day, Dr Fredrik Edfors participated in the poster session with a poster entitled "Gene specific correlation between protein and RNA"...Read more


Proteomic analysis of cell cycle progression reveal mitotic substages

2017-11-02
Affinity proteomics Cell Atlas Cell cycle Immunofluorescence

Examples of spindle phenotypes (Bipole, Collapsed, Multipole and Monopole)

A key feature and a critical first step in understanding cell division and proliferation lies in characterizing the temporal regulation of protein abundance. A collaborative publication "Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS" was recently published in eLife.

The Cell atlas team from Sweden joined forces with Dr Tony Ly and Professor Angus Lamond from the University of Dundee, to perform a proteome-wide analysis of changes in protein abundance and phosphorylation across the cell cycle...Read more


Conference - plenary lecture at Clinical Proteomics, Postgenome Medicine, Moscow, Russia.

2017-10-27
Conference Human Protein Atlas Precision medicine Tissue Atlas

Dr Cecilia Lindskog, Director of the Tissue Atlas in the Human Protein Atlas, will present a plenary lecture on October 31 entitled "The Human Protein Atlas - implications for human biology and precision medicine" on the Clinical Proteomics, Postgenome Medicine conference in Moscow, Russia. Dr Lindskog is highlighted as one of the key speakers of the conference. The 300+ international participants include medical advisors, scientists and business representatives, and the focus of the conference is to open the fields of "omics" science (genomics, transcriptomics, proteomics, metabolomics) to clinical practioners...Read more


Chan Zuckerberg funds pilot project within the Human Protein Atlas

2017-10-19
Cell Atlas Chan Zucherberg Initiative Human Protein Atlas

The Human Protein Atlas at the Science for Life Laboratory (SciLifeLab) are teaming up with the Chan Zuckerberg Initiative to strengthen research in cell biology and proteomics.

The Chan Zuckerberg Initiative, which was founded by Facebook founder Mark Zuckerberg and his wife, Dr. Priscilla Chan, provides financial and engineering support for the Human Cell Atlas, an ambitious international collaboration that aims to create a reference atlas of all cells in the healthy human body as a resource for studies of health and disease...Read more