The image of the month is a fluorescent antibody-based display of the glomerulus; the main filtrating unit within the kidney generated in the HPA group in Uppsala. The image is a result of a multiplex immunohistochemistry staining, where the podocyte protein podocin (gene: NPHS2) and five other proteins specific to different main structures within the kidney were stained and visualized through fluorescently tagged antibodies...Read more
In a recent publication in Nature Cell Biology, an integrated single-cell RNA sequencing and spatial transcriptomics strategy was used to clarify the origins and mechanisms behind cell heterogeneity in lung. The results were used to create a topographic atlas of early human lung development...Read more
The exploration of the human proteome has revealed many uncharacterized proteins with very interesting distributions in tissues and cells. Among them are many receptor proteins with unknown functions and predominant expression in the brain, including the orphan receptor GPR151...Read more
In the depths of our being, A microscopic world we cannot see, Where proteins reign supreme, And bring us to our knees.
The Human Protein Atlas, A treasure trove of information, Shows us the complexity, Of our cellular nation.
Each protein has a purpose, A task it must perform, To keep us healthy and strong, And shield us from harm.
Some proteins build our muscles, Others help us breathe, Some regulate our hormones, And make our bodies seethe.
The Human Protein Atlas, A guidebook to our core, Unravels the mysteries, That we've never known before...Read more
In this movie Professor Tomas Hökfelt (Karolinska Institutet) takes you on a journey to the areas of the brain affected by Alzheimer's disease...Read more
The version 23 of the Human Protein Atlas is based on an updated genome assembly and features a new Interaction sectionJune 19, 2023