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Integrated networks for obese subjects

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In a paper in a recent issue of Cell Metabolism, Human Protein Atlas-researchers investigate the biological processes that are altered in obese subjects.

Obesity is associated with an increased risk for a wide range of morbidities, including insulin resistance, type 2 diabetes, non-alcoholic fatty liver disease, and cardiovascular disease. Although the prevalence of obesity continues to dramatically increase worldwide, a clear understanding of the underlying molecular mechanisms involved in the progression of associated disorders is still lacking...Read more


The housekeeping proteome

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A large number of proteins are needed in all cells throughout the human body. These proteins are sometimes called housekeeping proteins, suggesting that their expression is crucial for the maintenance of basic functionality of all normally functioning cells.

A transcriptomics analysis shows that about 9,000 genes are expressed in all tissues and are therefore expected to fulfill these tasks, such as gene expression, metabolism, and cell structure.

As for gene expression, it is easily understood that every cell must have proteins that are involved in the genetic machinery of translating DNA to functional proteins, like RNA polymerases and ribosomal proteins...Read more


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WIRM XIV

March 4, 2020 - March 7, 2020

Mathias Uhlén, Petter Brodin and Fredrik Edfors will participate in the World Immune Regulation Meeting XIV in Davos.

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FEBS Practical and Lecture Course

June 21, 2020 - June 26, 2020

FEBS Practical and Lecture Course - A summer school aimed at graduate students, post-docs, and young independent investigators who want to learn about new techniques to explore the proteins encoded by the human genome.

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