BETA
CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Medium
Glial cells: Low
Neuronal cells: Low
Neuropil: Medium
RNA expressioni
Consensus:1796.2 nTPM
HPA:1473.0 nTPM
HPA Brain:2803.7 nTPM
HPA PFC Brain:1920.6 nTPM
GTEx:1796.2 nTPM
FANTOM5:4724.4 Scaled Tags Per Million
Macaque:1330.2 nTPM
Mouse:1863.6 nTPM
Pig:1818.3 nTPM
CEREBRAL CORTEX - SINGLE NUCLEI RNA EXPRESSIONi

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NEURONSi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 490
c-1 Excitatory (VGLUT1) CUX2+
c-2 Inhibitory (GAD1/2) LHX6+ T...
c-3 Inhibitory (GAD1/2) CXCL14+...
c-4 Inhibitory (GAD1/2) LHX6+ T...
c-5 Inhibitory (GAD1/2) CXCL14+
c-6 Excitatory (VGLUT1) FOXP2+
c-7 Excitatory (VGLUT1) CUX2+
c-8 Excitatory (VGLUT1)
c-9 Inhibitory (GAD1/2) LHX6+ T...
c-10 Inhibitory (GAD1/2) CXCL14+...
c-11 Inhibitory (GAD1/2) CXCL14+...
c-12 Excitatory (VGLUT1) FOXP2+
c-13 Excitatory (VGLUT1) FOXP2+
c-14 Excitatory (VGLUT1) CUX2+
c-15 Excitatory (VGLUT1) FOXP2+
c-16 Inhibitory (GAD1/2) CXCL14+...
c-17 Excitatory (VGLUT1/2)
c-18 Excitatory (VGLUT1) FOXP2+
c-19 Excitatory (VGLUT1/2) CUX2+
c-20 Inhibitory (GAD1/2) LAMP5+ ...
c-21 Excitatory (VGLUT1) FOXP2+
c-22 Inhibitory (GAD1/2) CXCL14+
c-23 Excitatory (VGLUT1) FOXP2+
c-24 Excitatory (VGLUT1) SOX5+
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NON-NEURONALi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 2330
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Oligodendrocyte progenitor ...
c-4 Oligodendrocytes
c-5 Astrocytes
c-6 Astrocytes
c-7 Microglia
c-8 Oligodendrocyte progenitor ...
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Astrocytes
c-12 Astrocytes
c-13 Astrocytes
c-14 Microglia
c-15 Vascular endothelial cells
c-16 Fibroblasts
c-17 Oligodendrocytes (CNTN1+)
c-18 Macrophages
c-19 Immature oligodendrocytes
c-20 Oligodendrocyte progenitor ...
c-21 Pericytes
c-22 Lymphocytes
c-23 Fibroblasts
c-24 Vascular smooth muscle cell
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

CEREBRAL CORTEX - Antibody stainingi
Antibody CAB002621
Endothelial cells Medium
Glial cells Low
Neuronal cells Low
Neuropil Medium



CEREBRAL CORTEX - PROTEINTALKS DB MS
Median intensity 2058542
Sample Intensity
Cerebral cortex_01
 1987327
Cerebral cortex_02
 1825997
Cerebral cortex_03
 1701132
Cerebral cortex_04
 2115432
Cerebral cortex_05
 2047379
Cerebral cortex_06
 2038609
Cerebral cortex_07
 1373406
Cerebral cortex_08
 1788845
Cerebral cortex_09
 2525450
Cerebral cortex_10
 2120766
Cerebral cortex_11
 1927067
Cerebral cortex_12
 2069706
Cerebral cortex_13
 2091311
Cerebral cortex_14
 1981499
Cerebral cortex_15
 1944173
Cerebral cortex_16
 2094517
Cerebral cortex_17
 1865663
Cerebral cortex_18
 1691063
Cerebral cortex_19
 1668507
Cerebral cortex_20
 1691862
Cerebral cortex_21
 2174006
Cerebral cortex_22
 1923660
Cerebral cortex_23
 1766325
Cerebral cortex_24
 2017394
Cerebral cortex_25
 1659625
Cerebral cortex_26
 2488401
Cerebral cortex_27
 1843940
Cerebral cortex_28
 3061494
Cerebral cortex_29
 3171924
Cerebral cortex_30
 3443430
Cerebral cortex_31
 2590957
Cerebral cortex_32
 2706713
Cerebral cortex_33
 2091761
Cerebral cortex_34
 2831031
Cerebral cortex_35
 2627120
Cerebral cortex_36
 2582135
Cerebral cortex_37
 2481164
Cerebral cortex_38
 2881734

CEREBRAL CORTEX - MANN MS
Median intensity ND
Replicate Intensity
Cerebral cortex_01
 ND
Cerebral cortex_02
 ND
Cerebral cortex_03
 ND

CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 1473.0
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 1249.6
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 1408.9
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 1760.4
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain Stereo-seq

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 2803.7
Sample id Sample description nTPM
Angular gyrus
nTPM: 1772.3
2103 Male, age 75, left hemisphere 2226.9
1790 Male, age 76, right hemisphere 1910.1
2260 Female, age 72, left hemisphere 1896.0
2221 Female, age 67, right hemisphere 1856.3
1866 Male, age 76, both hemispheres 1709.2
2602 Female, age 94, right hemisphere 1694.4
2265 Female, age 91, left hemisphere 1462.0
2722 Male, age 61, left hemisphere 1423.6
Angular gyrus (white matter)
nTPM: 1939.8
1920 Male, age 76, both hemispheres 1939.8
Anterior cingulate cortex, supragenual-dorsal
nTPM: 1626.7
1896 Female, age 85, right hemisphere 1733.4
2342 Female, age 94, right hemisphere 1617.1
2478 Female, age 67, right hemisphere 1611.2
2472 Male, age 75, left hemisphere 1608.3
2547 Male, age 74, left hemisphere 1563.6
Anterior cingulate cortex, supragenual-ventral
nTPM: 1587.5
1950 Female, age 85, right hemisphere 1830.4
1755 Female, age 94, right hemisphere 1668.0
2479 Female, age 67, right hemisphere 1578.2
1761 Male, age 74, left hemisphere 1474.0
2538 Male, age 75, left hemisphere 1386.9
Anterior insular cortex, dorsal
nTPM: 1632.2
2235 Female, age 91, right hemisphere 1921.1
2506 Female, age 94, right hemisphere 1736.2
2001 Male, age 76, right hemisphere 1487.6
2670 Male, age 75, left hemisphere 1383.8
Anterior insular cortex, ventral
nTPM: 1616.0
1925 Female, age 91, left hemisphere 1750.8
2262 Female, age 67, right hemisphere 1743.3
2596 Male, age 75, left hemisphere 1659.2
2507 Female, age 94, left hemisphere 1588.5
1852 Male, age 76, left hemisphere 1569.0
2757 Male, age 61, right hemisphere 1385.3
Area parastriata, inferior
nTPM: 1866.9
2234 Male, age 75, left hemisphere 2986.8
2509 Female, age 94, left hemisphere 2054.0
1758 Female, age 72, right hemisphere 2042.7
1789 Male, age 76, right hemisphere 1935.6
2268 Male, age 61, right hemisphere 1451.7
2421 Female, age 91, left hemisphere 1305.9
1760 Female, age 67, left hemisphere 1291.5
Area parastriata, parietal
nTPM: 1836.1
2236 Female, age 91, left hemisphere 2310.1
2420 Male, age 75, left hemisphere 2075.5
2233 Male, age 61, right hemisphere 1652.4
1785 Male, age 76, right hemisphere 1645.6
2680 Female, age 94, right hemisphere 1496.6
Area parastriata, superior
nTPM: 2065.8
2435 Male, age 61, left hemisphere 2756.0
2881 Male, age 76, left hemisphere 2369.7
1773 Female, age 91, left hemisphere 2135.5
2419 Male, age 75, right hemisphere 1950.6
2604 Female, age 94, right hemisphere 1849.4
2684 Female, age 67, left hemisphere 1333.7
Area parastriata, temporal
nTPM: 1608.8
1804 Male, age 76, right hemisphere 1836.7
2424 Female, age 67, left hemisphere 1625.7
2471 Male, age 75, left hemisphere 1607.2
2267 Male, age 61, right hemisphere 1528.6
2681 Female, age 94, right hemisphere 1445.7
Area striata
nTPM: 1535.6
1884 Male, age 76, left hemisphere 1861.8
2002 Female, age 91, right hemisphere 1796.3
1753 Female, age 72, right hemisphere 1737.9
2679 Female, age 94, right hemisphere 1445.7
2427 Female, age 91, left hemisphere 1265.5
2417 Male, age 61, right hemisphere 1106.5
Area striata (white matter)
nTPM: 2059.6
2258 Female, age 91, left hemisphere 2059.6
Claustrum
nTPM: 1697.7
1956 Male, age 74, unknown 1964.9
2196 Female, age 79, unknown 1964.6
2198 Male, age 80, both hemispheres 1935.0
2292 Female, age 85, both hemispheres 1876.4
2491 Male, age 75, both hemispheres 1583.4
2284 Female, age 91, both hemispheres 1569.6
2392 Female, age 94, both hemispheres 1543.7
2568 Male, age 61, both hemispheres 1481.5
2645 Female, age 72, unknown 1360.1
Corpus callosum, genu (white matter)
nTPM: 2141.9
2771 Male, age 75, left hemisphere 2889.9
1886 Female, age 67, right hemisphere 2767.6
1887 Male, age 76, left hemisphere 2218.4
1934 Male, age 61, right hemisphere 1789.5
1849 Female, age 91, right hemisphere 1780.7
1885 Female, age 94, left hemisphere 1405.4
Corpus callosum, splenium (white matter)
nTPM: 2803.7
2847 Female, age 67, right hemisphere 4010.9
2104 Male, age 75, left hemisphere 3402.0
1946 Male, age 76, left hemisphere 2200.1
2238 Female, age 94, right hemisphere 1601.8
Frontal eye field
nTPM: 1552.3
2761 Female, age 94, left hemisphere 1810.7
2441 Male, age 75, left hemisphere 1554.3
2543 Male, age 74, left hemisphere 1536.4
2147 Male, age 61, left hemisphere 1307.9
Frontal operculum
nTPM: 1743.3
2348 Male, age 75, left hemisphere 1953.2
2781 Female, age 85, right hemisphere 1643.9
2030 Male, age 61, right hemisphere 1632.8
Fusiform gyrus
nTPM: 1831.0
2784 Female, age 85, left hemisphere 2286.6
2074 Female, age 91, left hemisphere 1989.2
1807 Male, age 76, left hemisphere 1873.8
2617 Female, age 94, left hemisphere 1713.7
2431 Male, age 75, right hemisphere 1684.5
2433 Female, age 72, left hemisphere 1654.0
2112 Male, age 80, both hemispheres 1614.8
Inferior frontal gyrus, opercular
nTPM: 1788.7
2874 Female, age 85, right hemisphere 2124.1
2873 Female, age 85, left hemisphere 2007.9
2868 Male, age 75, right hemisphere 1856.0
2871 Female, age 94, left hemisphere 1838.7
2872 Female, age 94, right hemisphere 1816.6
2866 Male, age 61, right hemisphere 1783.7
2875 Female, age 67, left hemisphere 1718.9
2865 Male, age 61, left hemisphere 1688.1
2867 Male, age 75, left hemisphere 1578.9
2869 Male, age 74, left hemisphere 1473.8
Inferior parietal lobule
nTPM: 1563.2
2876 Male, age 76, right hemisphere 1827.9
2599 Female, age 94, left hemisphere 1510.2
2418 Male, age 75, left hemisphere 1491.1
2606 Female, age 67, right hemisphere 1423.6
Inferior temporal gyrus
nTPM: 1694.8
1808 Male, age 76, left hemisphere 1859.5
1970 Female, age 85, right hemisphere 1773.1
1965 Female, age 91, left hemisphere 1710.7
1880 Male, age 80, right hemisphere 1709.1
2430 Male, age 75, right hemisphere 1574.4
2689 Female, age 94, right hemisphere 1542.3
Intraparietal deep sulcus
nTPM: 1575.8
2798 Male, age 76, left hemisphere 1696.6
2600 Female, age 94, right hemisphere 1605.1
2102 Female, age 91, left hemisphere 1593.9
2669 Male, age 75, left hemisphere 1540.7
2607 Female, age 67, right hemisphere 1522.8
2230 Male, age 61, right hemisphere 1495.5
Lingual gyrus
nTPM: 1607.9
2073 Female, age 85, left hemisphere 1776.4
2838 Male, age 80, right hemisphere 1662.8
2618 Female, age 94, left hemisphere 1635.1
1893 Male, age 76, left hemisphere 1538.9
2688 Male, age 75, right hemisphere 1426.6
Middle cingulate cortex
nTPM: 1531.5
2640 Female, age 94, right hemisphere 1719.7
2028 Female, age 85, left hemisphere 1714.9
2357 Female, age 67, right hemisphere 1554.0
2539 Male, age 75, left hemisphere 1473.8
2633 Male, age 74, left hemisphere 1195.2
Middle temporal gyrus
nTPM: 1683.5
1799 Male, age 76, left hemisphere 1872.3
1819 Male, age 80, right hemisphere 1845.7
2616 Female, age 94, left hemisphere 1691.3
2034 Female, age 91, right hemisphere 1545.4
2611 Male, age 75, right hemisphere 1463.0
Occipital cortex
nTPM: 1435.6
1842 Male, age 76, right hemisphere 1589.4
2677 Female, age 67, right hemisphere 1507.9
2608 Female, age 67, both hemispheres 1469.6
2470 Male, age 75, right hemisphere 1327.3
2426 Male, age 75, midline 1283.7
Occipital cortex (white matter)
nTPM: 2575.9
2259 Male, age 75, midline 3200.2
2257 Female, age 67, both hemispheres 1951.7
Olfactory area
nTPM: 1758.4
1805 Female, age 85, right hemisphere 2040.8
2756 Female, age 67, right hemisphere 1901.1
2222 Female, age 67, right hemisphere 1896.3
2352 Female, age 94, right hemisphere 1785.8
2440 Male, age 75, left hemisphere 1632.7
2542 Male, age 74, left hemisphere 1293.8
Olfactory tubercle
nTPM: 1673.9
1846 Male, age 80, right hemisphere 1827.6
1998 Female, age 91, both hemispheres 1759.0
2487 Female, age 94, left hemisphere 1689.6
2856 Male, age 75, right hemisphere 1419.5
Orbitofrontal gyrus, anterior
nTPM: 2092.9
2863 Female, age 85, right hemisphere 3010.2
2864 Female, age 67, left hemisphere 1722.9
2862 Female, age 85, left hemisphere 1545.6
Paracentral lobule, anterior
nTPM: 1866.0
1776 Female, age 85, right hemisphere 2489.7
2340 Female, age 67, right hemisphere 2031.7
1754 Male, age 75, left hemisphere 1839.3
2638 Female, age 94, right hemisphere 1740.1
2474 Male, age 74, left hemisphere 1559.3
1926 Male, age 61, left hemisphere 1535.8
Paracentral lobule, posterior
nTPM: 1720.6
1775 Female, age 85, right hemisphere 2168.2
1764 Male, age 74, right hemisphere 1917.6
2551 Female, age 94, right hemisphere 1814.2
2446 Male, age 75, left hemisphere 1408.3
2345 Male, age 61, left hemisphere 1294.6
Parahippocampal cortex (white matter)
nTPM: 1747.7
2157 Female, age 91, both hemispheres 1747.7
Parietal operculum
nTPM: 1624.2
2719 Male, age 75, left hemisphere 1829.8
2356 Female, age 67, right hemisphere 1640.9
2552 Female, age 94, right hemisphere 1629.8
1763 Male, age 74, left hemisphere 1396.2
Parieto-insular cortex
nTPM: 1542.8
1976 Female, age 91, right hemisphere 2036.7
2831 Male, age 76, right hemisphere 1652.1
2508 Female, age 94, right hemisphere 1460.3
2232 Male, age 61, right hemisphere 1312.1
2671 Male, age 75, left hemisphere 1253.1
Parieto-occipital transitional area
nTPM: 1530.6
1784 Male, age 76, right hemisphere 1800.2
2468 Male, age 75, left hemisphere 1678.7
2674 Female, age 94, right hemisphere 1470.0
2270 Male, age 61, right hemisphere 1459.7
2683 Female, age 67, left hemisphere 1244.4
Parieto-temporal junction (white matter)
nTPM: 2536.4
1935 Female, age 94, right hemisphere 3284.2
1999 Female, age 67, right hemisphere 3004.9
2469 Male, age 75, right hemisphere 2550.6
2774 Male, age 61, right hemisphere 2305.6
2121 Male, age 76, left hemisphere 2295.2
2770 Female, age 91, right hemisphere 1778.0
Piriform cortex
nTPM: 1950.1
2347 Male, age 75, right hemisphere 2421.5
2153 Female, age 85, left hemisphere 1478.8
Postcentral gyrus
nTPM: 1734.6
2533 Male, age 75, right hemisphere 1734.6
Postcentral gyrus, dorsal
nTPM: 1906.7
2339 Female, age 67, right hemisphere 2590.2
2477 Female, age 94, right hemisphere 2095.6
1836 Female, age 85, right hemisphere 2060.5
2350 Male, age 75, left hemisphere 1863.2
2151 Male, age 61, left hemisphere 1453.3
2544 Male, age 74, left hemisphere 1377.7
Postcentral gyrus, middle
nTPM: 1682.3
2146 Female, age 67, right hemisphere 1848.9
2545 Male, age 74, left hemisphere 1810.1
1897 Female, age 85, right hemisphere 1653.9
2444 Male, age 75, left hemisphere 1551.2
2248 Male, age 61, left hemisphere 1547.6
Postcentral gyrus, ventral
nTPM: 1759.7
2445 Male, age 75, left hemisphere 1886.2
2836 Female, age 94, right hemisphere 1810.1
2024 Female, age 85, right hemisphere 1583.0
Posterior cingulate cortex
nTPM: 1920.4
1759 Male, age 74, right hemisphere 2324.6
2553 Female, age 94, right hemisphere 1950.5
2473 Male, age 75, left hemisphere 1485.9
Posterior cingulate cortex, dorsal
nTPM: 1536.3
2343 Male, age 61, left hemisphere 1853.4
2641 Female, age 94, right hemisphere 1752.2
2076 Female, age 85, right hemisphere 1675.5
2556 Female, age 67, right hemisphere 1612.7
2540 Male, age 75, right hemisphere 1209.4
2634 Male, age 74, left hemisphere 1114.6
Posterior cingulate cortex, ventral
nTPM: 1525.1
2448 Female, age 67, right hemisphere 1817.9
1994 Female, age 85, right hemisphere 1605.4
1762 Female, age 94, right hemisphere 1599.3
2541 Male, age 75, right hemisphere 1586.7
2346 Male, age 61, left hemisphere 1361.1
2635 Male, age 74, left hemisphere 1180.2
Posterior insular cortex
nTPM: 1566.4
2832 Female, age 91, right hemisphere 1965.7
2603 Female, age 94, left hemisphere 1782.2
2511 Female, age 67, right hemisphere 1583.0
1823 Male, age 76, right hemisphere 1506.3
2597 Male, age 75, left hemisphere 1317.3
2231 Male, age 61, left hemisphere 1243.8
Precentral gyrus
nTPM: 1406.5
2557 Male, age 75, right hemisphere 1406.5
Precentral gyrus, dorsal
nTPM: 1804.3
2476 Female, age 94, right hemisphere 2067.7
1756 Male, age 74, left hemisphere 1846.9
2442 Male, age 75, left hemisphere 1826.0
2354 Female, age 67, right hemisphere 1476.7
Precentral gyrus, middle
nTPM: 1857.9
1969 Female, age 67, right hemisphere 2204.5
2443 Male, age 75, left hemisphere 2022.0
2475 Male, age 74, right hemisphere 1804.9
2549 Female, age 94, right hemisphere 1705.4
1909 Male, age 61, left hemisphere 1552.8
Precentral gyrus, ventral
nTPM: 1671.6
2662 Female, age 67, right hemisphere 2061.6
2550 Female, age 94, right hemisphere 1597.5
2630 Male, age 75, left hemisphere 1517.6
2678 Male, age 74, left hemisphere 1509.7
Precuneus
nTPM: 1606.3
1782 Male, age 76, right hemisphere 1824.2
2467 Male, age 75, right hemisphere 1753.9
1780 Female, age 91, right hemisphere 1653.8
2510 Female, age 67, right hemisphere 1484.6
2673 Female, age 94, right hemisphere 1480.6
2594 Male, age 61, left hemisphere 1440.6
Premotor cortex, dorsal
nTPM: 1656.2
2554 Female, age 67, right hemisphere 1958.4
1878 Female, age 85, right hemisphere 1749.5
2027 Male, age 61, left hemisphere 1582.7
2536 Male, age 75, left hemisphere 1561.1
2631 Male, age 74, left hemisphere 1429.3
Premotor cortex, ventral
nTPM: 1797.0
1777 Female, age 67, left hemisphere 2466.5
1779 Male, age 61, left hemisphere 1871.9
2637 Female, age 94, right hemisphere 1748.3
2349 Male, age 75, left hemisphere 1676.2
1881 Female, age 85, right hemisphere 1671.4
1757 Male, age 74, left hemisphere 1347.7
Retrosplenial cortex
nTPM: 1892.6
1914 Male, age 76, right hemisphere 2179.6
1951 Male, age 61, right hemisphere 2096.8
2675 Female, age 94, left hemisphere 1401.5
Somatomor cortex, precentral gyrus (white matter)
nTPM: 1717.3
2439 Male, age 75, right hemisphere 1717.3
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 1858.2
2623 Male, age 75, right hemisphere 1858.2
Subcentral gyrus, S2
nTPM: 1603.8
1964 Female, age 85, right hemisphere 1691.5
2839 Female, age 94, right hemisphere 1658.1
2351 Male, age 75, left hemisphere 1653.2
2762 Male, age 74, left hemisphere 1645.1
2072 Male, age 61, left hemisphere 1529.8
2555 Female, age 67, right hemisphere 1445.0
Superior parietal lobule
nTPM: 1650.3
1800 Male, age 76, right hemisphere 2048.3
1992 Female, age 91, right hemisphere 1706.7
2672 Female, age 94, right hemisphere 1580.7
2229 Male, age 61, right hemisphere 1465.4
2605 Female, age 67, right hemisphere 1450.3
Superior temporal gyrus
nTPM: 1642.9
1844 Female, age 91, left hemisphere 2079.0
2615 Female, age 94, left hemisphere 1824.4
1843 Male, age 76, left hemisphere 1676.3
2025 Male, age 80, right hemisphere 1406.3
2687 Male, age 75, right hemisphere 1228.7
Supplementary motor cortex
nTPM: 1466.7
2548 Female, age 94, right hemisphere 1637.0
1993 Male, age 61, left hemisphere 1474.9
2632 Male, age 74, left hemisphere 1420.7
2537 Male, age 75, left hemisphere 1334.1
Supramarginal gyrus
nTPM: 1573.7
1798 Male, age 76, right hemisphere 1734.8
1991 Female, age 91, right hemisphere 1627.1
2601 Female, age 94, left hemisphere 1583.1
2513 Female, age 72, left hemisphere 1572.5
2415 Male, age 61, left hemisphere 1351.0
Temporal pole
nTPM: 1911.4
1832 Female, age 91, left hemisphere 2336.9
1853 Female, age 85, right hemisphere 2067.5
2518 Male, age 75, right hemisphere 1869.9
2612 Female, age 94, left hemisphere 1654.2
1826 Male, age 76, right hemisphere 1628.5
Temporal white matter
nTPM: 2219.5
2736 Female, age 91, right hemisphere 2785.3
2254 Male, age 75, right hemisphere 2582.1
1801 Male, age 76, left hemisphere 2396.4
2524 Female, age 85, left hemisphere 1723.1
2523 Female, age 94, left hemisphere 1610.7
Temporo-insular cortex, parainsular gyrus
nTPM: 1563.9
2264 Female, age 91, right hemisphere 1852.7
1802 Male, age 76, left hemisphere 1668.2
2512 Female, age 67, right hemisphere 1646.3
2598 Male, age 75, left hemisphere 1576.8
2676 Female, age 94, right hemisphere 1338.6
2416 Male, age 61, right hemisphere 1301.0
Temporo-occipital transitional zone
nTPM: 1862.4
1900 Male, age 76, left hemisphere 2054.2
1793 Male, age 80, right hemisphere 1952.5
2251 Female, age 85, right hemisphere 1580.5
Transversal temporal gyrus, anterior
nTPM: 1656.8
2522 Female, age 94, left hemisphere 1861.1
1888 Female, age 91, left hemisphere 1789.3
1809 Male, age 76, right hemisphere 1740.5
1910 Male, age 80, right hemisphere 1507.5
2610 Male, age 75, right hemisphere 1385.9
Transversal temporal gyrus, posterior
nTPM: 1682.7
1967 Female, age 91, right hemisphere 2029.9
2614 Female, age 94, left hemisphere 1742.8
2833 Male, age 80, right hemisphere 1608.7
2520 Male, age 75, right hemisphere 1597.3
1922 Male, age 76, left hemisphere 1434.9

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 1920.6
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 1318.1
1516 Female, age 85, left hemisphere 2053.7
1512 Male, age 75, left hemisphere 1488.3
1514 Male, age 74, right hemisphere 1425.6
1517 Female, age 67, left hemisphere 1386.2
1518 Female, age 67, right hemisphere 1251.8
1513 Male, age 74, left hemisphere 1179.2
1511 Male, age 61, right hemisphere 1175.9
1510 Male, age 61, left hemisphere 1158.6
1515 Female, age 94, right hemisphere 743.7
Anterior cingulate gyrus, pregenual-ventral
nTPM: 1369.3
1521 Male, age 74, left hemisphere 1616.1
1523 Female, age 67, left hemisphere 1465.5
1522 Male, age 74, right hemisphere 1383.1
1520 Male, age 75, right hemisphere 1231.9
1519 Male, age 61, left hemisphere 1149.9
Anterior cingulate gyrus, subgenual
nTPM: 1355.7
1529 Female, age 85, left hemisphere 1874.0
1530 Female, age 67, right hemisphere 1437.1
1527 Male, age 74, left hemisphere 1342.7
1526 Male, age 75, right hemisphere 1316.8
1528 Male, age 74, right hemisphere 1268.6
1524 Male, age 61, left hemisphere 1138.5
1525 Male, age 75, left hemisphere 1112.0
Dorsolateral prefrontal cortex
nTPM: 1599.2
1450 Female, age 67, right hemisphere 2426.4
1449 Female, age 85, right hemisphere 1840.2
1446 Male, age 74, right hemisphere 1789.0
1444 Male, age 75, left hemisphere 1679.4
1445 Male, age 75, right hemisphere 1484.6
1447 Female, age 94, left hemisphere 1015.9
1448 Female, age 94, right hemisphere 959.1
Dorsomedial prefrontal cortex
nTPM: 1920.6
1442 Male, age 75, right hemisphere 3707.4
1441 Male, age 75, left hemisphere 2168.3
1443 Female, age 67, right hemisphere 1588.9
1439 Male, age 61, left hemisphere 1234.6
1440 Male, age 61, right hemisphere 903.6
Frontomarginal cortex
nTPM: 1493.8
1471 Female, age 85, left hemisphere 2869.3
1468 Male, age 74, left hemisphere 1590.9
1472 Female, age 67, left hemisphere 1550.3
1467 Male, age 75, right hemisphere 1546.5
1473 Female, age 67, right hemisphere 1404.5
1466 Male, age 61, right hemisphere 1217.9
1469 Female, age 94, left hemisphere 1167.7
1465 Male, age 61, left hemisphere 1052.2
1470 Female, age 94, right hemisphere 1045.3
Frontopolar cortex
nTPM: 1350.6
1461 Male, age 75, right hemisphere 1984.4
1460 Male, age 75, left hemisphere 1664.3
1463 Female, age 67, left hemisphere 1405.1
1464 Female, age 67, right hemisphere 1341.0
1459 Male, age 61, right hemisphere 1170.9
1462 Female, age 94, left hemisphere 986.3
1458 Male, age 61, left hemisphere 901.8
Gyrus rectus
nTPM: 1347.6
1480 Female, age 85, left hemisphere 1906.4
1477 Male, age 75, right hemisphere 1656.4
1474 Male, age 61, left hemisphere 1445.9
1476 Male, age 75, left hemisphere 1419.4
1481 Female, age 67, left hemisphere 1386.9
1475 Male, age 61, right hemisphere 1144.0
1479 Female, age 94, right hemisphere 996.2
1478 Female, age 94, left hemisphere 825.7
Inferior frontal gyrus, orbital
nTPM: 1757.4
1507 Female, age 85, left hemisphere 4943.1
1505 Male, age 74, right hemisphere 2180.2
1504 Male, age 74, left hemisphere 1668.0
1503 Male, age 75, right hemisphere 1525.1
1509 Female, age 67, right hemisphere 1397.0
1508 Female, age 85, right hemisphere 1384.3
1502 Male, age 75, left hemisphere 1274.1
1500 Male, age 61, left hemisphere 1088.0
1501 Male, age 61, right hemisphere 1062.9
1506 Female, age 94, left hemisphere 1051.6
Inferior frontal gyrus, triangular
nTPM: 1396.4
1544 Male, age 75, right hemisphere 1785.6
1543 Male, age 61, right hemisphere 1545.1
1545 Male, age 74, right hemisphere 1518.7
1549 Female, age 67, left hemisphere 1495.7
1547 Female, age 85, left hemisphere 1438.3
1548 Female, age 85, right hemisphere 1268.4
1542 Male, age 61, left hemisphere 1150.5
1546 Female, age 94, right hemisphere 968.6
Orbitofrontal gyrus, lateral
nTPM: 1444.5
1497 Female, age 85, left hemisphere 3357.4
1499 Female, age 67, right hemisphere 1456.0
1494 Male, age 75, left hemisphere 1232.4
1498 Female, age 85, right hemisphere 1180.3
1496 Female, age 94, right hemisphere 1102.5
1493 Male, age 61, right hemisphere 930.1
1495 Female, age 94, left hemisphere 853.0
Orbitofrontal gyrus, medial
nTPM: 1477.1
1484 Male, age 75, right hemisphere 1868.9
1489 Female, age 85, left hemisphere 1735.3
1485 Male, age 74, left hemisphere 1727.1
1486 Male, age 74, right hemisphere 1615.1
1491 Female, age 67, left hemisphere 1604.2
1490 Female, age 85, right hemisphere 1556.3
1492 Female, age 67, right hemisphere 1499.4
1483 Male, age 75, left hemisphere 1436.1
1482 Male, age 61, left hemisphere 1337.4
1488 Female, age 94, right hemisphere 968.8
1487 Female, age 94, left hemisphere 899.7
Orbitofrontal gyrus, posterior
nTPM: 1475.4
1540 Female, age 67, left hemisphere 2269.6
1538 Female, age 85, left hemisphere 2059.9
1541 Female, age 67, right hemisphere 1900.3
1533 Male, age 75, left hemisphere 1620.5
1539 Female, age 85, right hemisphere 1598.0
1534 Male, age 75, right hemisphere 1366.0
1535 Male, age 74, left hemisphere 1295.7
1531 Male, age 61, left hemisphere 1105.7
1532 Male, age 61, right hemisphere 1035.7
1536 Female, age 94, left hemisphere 1009.0
1537 Female, age 94, right hemisphere 968.8
Subcallosal gyrus
nTPM: 1581.8
1550 Male, age 61, left hemisphere 2583.6
1553 Male, age 75, right hemisphere 2011.3
1558 Female, age 85, left hemisphere 1855.8
1561 Female, age 67, right hemisphere 1779.3
1552 Male, age 75, left hemisphere 1677.2
1560 Female, age 67, left hemisphere 1471.8
1555 Male, age 74, right hemisphere 1450.5
1551 Male, age 61, right hemisphere 1442.6
1559 Female, age 85, right hemisphere 1417.2
1554 Male, age 74, left hemisphere 1245.7
1557 Female, age 94, right hemisphere 1044.6
1556 Female, age 94, left hemisphere 1002.1
Superior frontal gyrus
nTPM: 1591.0
1569 Female, age 85, left hemisphere 2141.9
1570 Female, age 85, right hemisphere 2062.8
1566 Male, age 74, right hemisphere 1762.0
1565 Male, age 75, right hemisphere 1756.8
1564 Male, age 75, left hemisphere 1704.9
1571 Female, age 67, right hemisphere 1698.7
1562 Male, age 61, left hemisphere 1578.5
1563 Male, age 61, right hemisphere 1174.2
1567 Female, age 94, left hemisphere 1039.3
1568 Female, age 94, right hemisphere 990.4
Temporal cortex
nTPM: 1814.2
1591 Male, age 75, right hemisphere 3387.5
1593 Male, age 74, right hemisphere 1859.9
1592 Male, age 74, left hemisphere 1758.8
1596 Female, age 85, right hemisphere 1726.5
1590 Male, age 61, right hemisphere 1409.7
1595 Female, age 94, right hemisphere 1409.3
1594 Female, age 94, left hemisphere 1147.5
Ventrolateral prefrontal cortex
nTPM: 1522.1
1455 Female, age 85, right hemisphere 1888.7
1457 Female, age 67, right hemisphere 1785.1
1451 Male, age 75, right hemisphere 1639.8
1456 Female, age 67, left hemisphere 1569.1
1453 Male, age 74, right hemisphere 1560.0
1452 Male, age 74, left hemisphere 1229.0
1454 Female, age 94, left hemisphere 982.7
Ventromedial prefrontal cortex
nTPM: 1565.6
1436 Female, age 85, left hemisphere 2834.9
1432 Male, age 61, left hemisphere 1721.5
1438 Female, age 67, left hemisphere 1501.2
1437 Female, age 85, right hemisphere 1423.3
1433 Male, age 61, right hemisphere 1206.2
1434 Male, age 75, right hemisphere 1193.5
1435 Female, age 94, right hemisphere 1078.8

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 1796.2
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 1796.2
Samples: 233

Max nTPM: 3590.4
Min nTPM: 968.8
Std nTPM: 419.1
Median nTPM: 1750.5
GTEX-14E6C-0011-R3a-SM-G8W87 40-49 years, male 3590.4
GTEX-14BMV-0011-R3a-SM-5ZZU7 50-59 years, male 3557.5
GTEX-1PWST-0011-R3a-SM-F33ZZ 70-79 years, male 3339.3
GTEX-1I1GS-0011-R3b-SM-CYPS7 60-69 years, male 3207.6
GTEX-1R46S-0011-R3a-SM-F2TBG 60-69 years, female 3104.6
GTEX-1JMPZ-0011-R3a-SM-EYYWX 30-39 years, male 2847.7
GTEX-1MJK2-0011-R3a-SM-F2TBD 50-59 years, male 2697.7
GTEX-14JG1-0011-R3a-SM-62LEC 40-49 years, male 2672.2
GTEX-14LLW-0011-R3b-SM-62LFW 70-79 years, female 2661.2
GTEX-1RQED-0011-R3a-SM-F341T 60-69 years, male 2628.4
GTEX-1IKK5-0011-R3b-SM-C1YRY 60-69 years, male 2575.8
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Brain - Cortex
Average nTPM: 1545.5
Samples: 270

Max nTPM: 3400.2
Min nTPM: 991.9
Std nTPM: 265.5
Median nTPM: 1513.3
GTEX-OHPN-2526-SM-2I5H3 60-69 years, female 3400.2
GTEX-1PWST-3126-SM-EXUSE 70-79 years, male 3023.4
GTEX-15RJE-3026-SM-7KUM1 40-49 years, male 2560.6
GTEX-14C5O-3026-SM-5YYB2 60-69 years, male 2428.7
GTEX-ZYY3-3126-SM-5MR6M 60-69 years, female 2309.6
GTEX-132Q8-3026-SM-5PNVG 60-69 years, male 2300.8
GTEX-X4XY-3026-SM-EWRM9 60-69 years, male 2167.1
GTEX-1GN1U-3126-SM-9KNV6 50-59 years, female 2160.6
GTEX-1O9I2-3026-SM-E76PX 50-59 years, male 2088.9
GTEX-1H1ZS-3026-SM-9KNUJ 70-79 years, male 2081.1
GTEX-139T8-1026-SM-5J2MC 60-69 years, male 2015.3
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Brain - Frontal Cortex (BA9)
Average nTPM: 1666.7
Samples: 269

Max nTPM: 3289.9
Min nTPM: 940.7
Std nTPM: 362.6
Median nTPM: 1624.1
GTEX-1O9I2-0011-R10b-SM-F2I33 50-59 years, male 3289.9
GTEX-14PJO-0011-R10a-SM-686ZS 60-69 years, male 3162.3
GTEX-1R46S-0011-R10a-SM-F3416 60-69 years, female 3088.3
GTEX-1QMI2-0011-R10a-SM-F3428 60-69 years, male 3015.6
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 2784.5
GTEX-ZAK1-0011-R10a-SM-H7OGG 50-59 years, female 2714.1
GTEX-1CB4J-0011-R10a-SM-9WG63 60-69 years, male 2711.2
GTEX-1PWST-0011-R10a-SM-F2I37 70-79 years, male 2659.0
GTEX-1N2DW-0011-R10a-SM-F341J 50-59 years, male 2454.2
GTEX-13QJC-0011-R10a-SM-5SI63 60-69 years, female 2440.3
GTEX-1H1ZS-0011-R10b-SM-A9SK9 70-79 years, male 2398.4
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 4724.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 1445.5
FF:10163-103B1 76 years, female 1445.5
Postcentral gyrus
Scaled Tags Per Million: 4024.6
FF:10032-101E5 44-52 years, mixed 4024.6
Frontal lobe
Scaled Tags Per Million: 2959.3
FF:10040-101F4 32-61 years, mixed 2959.3
Insula
Scaled Tags Per Million: 3290.9
FF:10039-101F3 20-68 years, mixed 3290.9
Medial frontal gyrus
Scaled Tags Per Million: 1543.4
FF:10150-102I6 76 years, female 1543.4
Medial temporal gyrus
Scaled Tags Per Million: 2100.8
FF:10183-103D3 60 years, female 2596.5
FF:10156-103A3 76 years, female 1605.1
Occipital lobe
Scaled Tags Per Million: 3747.6
FF:10076-102A4 27 years, male 3747.6
Occipital pole
Scaled Tags Per Million: 4561.6
FF:10036-101E9 22-68 years, mixed 4561.6
Paracentral gyrus
Scaled Tags Per Million: 3435.4
FF:10035-101E8 22-69 years, mixed 3435.4
Parietal lobe
Scaled Tags Per Million: 2247.0
FF:10034-101E7 35-89 years, mixed 3222.8
FF:10171-103B9 60 years, female 2077.7
FF:10157-103A4 76 years, female 1440.6
Temporal lobe
Scaled Tags Per Million: 4724.4
FF:10031-101E4 32-61 years, mixed 4724.4

CEREBRAL CORTEX - Macaque RNA-seq
Max subtype nTPMi 1330.2
Macaque sample Sample description nTPM
Angular gyrus
nTPM: 1002.9
Samples: 1

Max nTPM: 1002.9
Min nTPM: 1002.9
Sample A 1002.9
Claustrum
nTPM: 1330.2
Samples: 1

Max nTPM: 1330.2
Min nTPM: 1330.2
Sample B 1330.2
Fusiform gyrus
nTPM: 1120.4
Samples: 2

Max nTPM: 1288.2
Min nTPM: 952.6
Sample A 952.6
Sample B 1288.2
Inferior temporal gyrus
nTPM: 888.7
Samples: 2

Max nTPM: 962.2
Min nTPM: 815.2
Sample A 815.2
Sample B 962.2
Middle temporal gyrus
nTPM: 1103.7
Samples: 2

Max nTPM: 1218.4
Min nTPM: 988.9
Sample A 1218.4
Sample B 988.9
Postcentral gyrus
nTPM: 1111.0
Samples: 2

Max nTPM: 1268.3
Min nTPM: 953.6
Sample A 953.6
Sample B 1268.3
Posterior cingulate cortex
nTPM: 1055.9
Samples: 2

Max nTPM: 1128.1
Min nTPM: 983.6
Sample A 983.6
Sample B 1128.1
Precentral gyrus
nTPM: 1255.5
Samples: 3

Max nTPM: 1330.5
Min nTPM: 1133.9
Sample A 1133.9
Sample B 1302.0
Sample C 1330.5
Superior parietal lobule
nTPM: 967.3
Samples: 2

Max nTPM: 983.3
Min nTPM: 951.4
Sample A 951.4
Sample B 983.3
Superior temporal gyrus
nTPM: 924.6
Samples: 2

Max nTPM: 985.9
Min nTPM: 863.2
Sample A 863.2
Sample B 985.9
Supramarginal gyrus
nTPM: 1130.0
Samples: 2

Max nTPM: 1170.0
Min nTPM: 1089.9
Sample A 1089.9
Sample B 1170.0
Gyrus rectus
nTPM: 1070.4
Samples: 2

Max nTPM: 1118.3
Min nTPM: 1022.5
Sample A 1022.5
Sample B 1118.3
Insular cortex
nTPM: 1085.7
Samples: 2

Max nTPM: 1158.8
Min nTPM: 1012.6
Sample A 1158.8
Sample B 1012.6
Superior frontal gyrus
nTPM: 1246.1
Samples: 2

Max nTPM: 1504.1
Min nTPM: 988.0
Sample A 988.0
Sample B 1504.1

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 1818.3
Pig sample Sample description nTPM
Occipital cortex
nTPM: 1607.9
Samples: 4

Max nTPM: 1965.7
Min nTPM: 1272.1
Sample A Female 1634.9
Sample B Female 1272.1
Sample C Male 1965.7
Sample D Male 1559.1
Retrosplenial cortex
nTPM: 1470.4
Samples: 4

Max nTPM: 1697.1
Min nTPM: 1257.1
Sample A Female 1659.0
Sample B Female 1257.1
Sample C Male 1697.1
Sample D Male 1268.2
Cingulate cortex
nTPM: 1471.3
Samples: 4

Max nTPM: 1796.3
Min nTPM: 1117.8
Sample A Female 1796.3
Sample B Female 1117.8
Sample C Male 1664.0
Sample D Male 1307.2
Insular cortex
nTPM: 1393.5
Samples: 4

Max nTPM: 1624.9
Min nTPM: 1187.4
Sample A Female 1624.9
Sample B Female 1214.3
Sample C Male 1547.4
Sample D Male 1187.4
Motor cortex
nTPM: 1677.3
Samples: 4

Max nTPM: 1862.7
Min nTPM: 1455.9
Sample A Female 1862.7
Sample B Female 1621.2
Sample C Male 1769.4
Sample D Male 1455.9
Prefrontal cortex
nTPM: 1532.1
Samples: 4

Max nTPM: 1601.6
Min nTPM: 1429.3
Sample A Female 1601.6
Sample B Female 1573.3
Sample C Male 1524.3
Sample D Male 1429.3
Somatosensory cortex
nTPM: 1818.3
Samples: 3

Max nTPM: 2018.5
Min nTPM: 1532.8
Sample B Female 1532.8
Sample C Male 1903.7
Sample D Male 2018.5
Temporal cortex
nTPM: 1496.6
Samples: 3

Max nTPM: 1557.7
Min nTPM: 1391.8
Sample A Female 1540.4
Sample B Female 1557.7
Sample D Male 1391.8

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 1863.6
Mouse sample Sample description nTPM
Motor and prefrontal cortex
nTPM: 1806.8
Samples: 4

Max nTPM: 1926.0
Min nTPM: 1755.7
Sample A 1782.1
Sample B 1755.7
Sample C 1926.0
Sample D 1763.3
Retrosplenial and cingulate cortex
nTPM: 1863.6
Samples: 3

Max nTPM: 1898.7
Min nTPM: 1801.2
Sample A 1898.7
Sample B 1890.9
Sample C 1801.2
Somatosensory cortex
nTPM: 1768.9
Samples: 4

Max nTPM: 1874.3
Min nTPM: 1642.5
Sample A 1874.3
Sample B 1642.5
Sample C 1869.5
Sample D 1689.1
Visual cortex
nTPM: 1714.1
Samples: 4

Max nTPM: 1783.8
Min nTPM: 1568.9
Sample A 1783.8
Sample B 1782.5
Sample C 1721.3
Sample D 1568.9

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