ANXA1

GENERAL INFORMATION

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Gene name

ANXA1

Gene description

Annexin A1

Protein class

Cancer-related genes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Transporters

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic, membranous and nuclear expression at variable levels in selected tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 5 antibodies.
HPA011271 , HPA011272 , CAB013023 , CAB035987 , CAB058693
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Esophagus

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ANXA1 (HGNC Symbol)

Synonyms

ANX1, LPC1

Description

Annexin A1 (HGNC Symbol)

Entrez gene summary

This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]

Chromosome

9

Cytoband

q21.13

Chromosome location (bp)

73151757 - 73170393

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135046 (version 78.38)

Entrez gene

301

UniProt

P04083 (UniProt - Evidence at protein level)

neXtProt

NX_P04083

Antibodypedia

ANXA1 antibodies


PROTEIN BROWSER

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ENST00000257497
 
ENST00000376911
 
ENST00000415424
 
ENST00000456643
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANXA1-002 ENSP00000257497
ENST00000257497
P04083
Show all »
Show » Show » 346 38.7 No 0
ANXA1-003 ENSP00000366109
ENST00000376911
P04083
Show all »
Show » Show » 346 38.7 No 0
ANXA1-004 ENSP00000412489
ENST00000456643
Q5T3N1
Show all »
Show » Show » 204 22.8 No 0
ANXA1-006 ENSP00000414013
ENST00000415424
Q5T3N0
Show all »
Show » Show » 115 12.6 No 0