In a recent publication in JCI Insight researchers from the Human Protein Atlas have described the expression of the currently known cancer-testis antigens (CTAs) in non-small cell lung cancer, and have added 50 new CTAs to this list.
Lung cancer is the most common cause of cancer related death in Sweden and worldwide. Most patient present with advanced disease and have a short life expectancy despite modern therapy.
Dijana Djureinovic is a PhD student in the group of Cecilia Lindskog at Science for Life Laboratory. She started her PhD studies two years ago, but worked in the project before that, on antibody validation...Read more
In the Human Protein Atlas, there are 32 human organs and tissues analyzed. 2489 of the genes have significantly higher expression in one tissue compared to all other tissue types. Analysis show that testis is the organ with the largest number of tissue-enriched genes, with 1057 genes classified as testis enriched. The specific events and alterations of cell structure during spermatogenesis, and the fact that sperm has the ability to survive outside the male body may explain why testis has the largest number of enriched genes.
The organ with the second highest number of enriched genes is the brain with 381 enriched genes...Read more
October 24, 2018 - October 28, 2018
Mathias Uhlen will present "The creation of a mammalian protein brain atlas" at the 13th International Conference on Genomics taking place in Shenzhen, China. His talk is scheduled at 15.20 on October 26. Programme
October 25, 2018 - October 26, 2018
Dr. Jochen Schwenk will give a talk on "Affinity-based assays for biomarkers of the plasma proteome", at the 14th Annual Workshop of Biofilms - Research Center for Biointerfaces, which focuses on Biomarkers - methods and technology.Programme